Senior Software Engineer - Deep Neurophenotyping

Mass General Brigham•Boston, MA

4d•Hybrid

About The Position

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. This is a part-time, 20 hour position. Software engineer to lead software development of the “Neurobooth” project, which is an effort to perform large scale digital phenotyping inside the Mass General neurology clinic. With funding from industry, government, and academic institutions, we have created a booth that is equipped with an array of devices, including consumer and industrial grade cameras, eye trackers, microphones, wearable sensors, and other sensors for physiological measurement. Patients perform motor and cognitive tasks inside the booth while collecting synchronized data from the devices. Sensor data are integrated with clinical data, organized in a database, and routed to a computing cluster for analysis. Data visualizations and summaries are generated in real-time to enable sharing of information with clinicians and patients in the clinic. This long-term project will generate the first dataset of its kind to support training of machine learning models and creation of tools to detect early signs of disease, precisely measure disease for clinical trials, and understand molecular and systems-level underpinnings of behavior in neurological diseases. The role requires an experienced and versatile software engineer, with hardware-integration experience, to ensure that the custom-built, Python-based platform controlling every aspect of Neurobooth is highly robust in a live clinical setting. The system is real-time and distributed, coordinating data acquisition, stimulus presentation, and synchronized recording across multiple networked machines and a wide array of hardware devices, so that reliability, precise timing, and disciplined engineering are essential. The engineer will apply software development best practices and maintain Neurobooth as an open-source project that any team in the world can use and build upon. Responsible for design, development, implementation, and support of advanced technical solutions, including platform systems that require critical aspects of infrastructure, network, application, database, and security frameworks.

Requirements

Bachelor's Degree Computer Science required or Bachelor's Degree Related Field of Study required
Experience as a systems engineer or related position 5-7 years required
Deep expertise in enterprise platform design, implementation, and optimization
Advanced automation and orchestration capabilities using tools like Ansible, Terraform, or similar
Proficient knowledge of cloud-native architectures and services.
Ability to conduct root cause analysis and performance tuning at the system and application levels
Proficient in designing and implementing high-availability and disaster recovery solutions
Familiarity with observability frameworks and modern monitoring/alerting platforms
Proven experience in developing system architecture documentation and operational runbooks
Ability to mentor junior engineers and lead cross-functional technical initiatives

Nice To Haves

hardware-integration experience

Responsibilities

Lead the design, deployment, and optimization of enterprise platforms and services.
Define and implement advanced automation and orchestration solutions.
Design and manage complex platforms in hybrid and multi-cloud environments.
Perform advanced troubleshooting and root cause analysis for critical platform issues.
Design and implement system monitoring and observability solutions.
Lead platform performance tuning and capacity planning efforts.
Develop technical standards, operational procedures, and leading practices.
Mentor junior engineers and provide technical guidance to project teams.