Senior Scientist

Bristol Myers Squibb • Devens, MA

11d • $123,120 - $149,196 • Onsite

About The Position

The Senior Scientist will be part of the Scale-up Lab in Devens, Massachusetts, and will report to the Director of Pilot Plant Network and External Manufacturing (PPNE). The role is responsible for scaling up and executing upstream and downstream processes for assets in the Biologics Development portfolio. The scientist will work with process, analytical, and manufacturing teams to improve internal process technology-transfer procedures and collaborate on new technology initiatives. The role also provides support, as needed, for external GMP-related activities, including investigations, deviations, CAPA, and change control. The work includes operating and supporting scale-up lab activities, preparing and reviewing technical documents, and contributing to process development and technology transfer for clinical and commercial manufacturing.

Requirements

• Ph.D. with 2–4 years of experience, M.S. with 4–6 years of experience, or B.S. with 7–9 years of experience in Chemical/Biochemical Engineering, Biochemistry, or a related field, with relevant industrial and/or academic experience.
• Strong knowledge of either upstream processing (mammalian cell culture) or downstream processing (harvest, chromatography, and filtration).
• Working knowledge of cGMP.
• Excellent oral and written communication skills.
• Ability to work well both as part of a team and independently.
• Prior experience in single-use manufacturing and automation.

Nice To Haves

• Prior experience with pilot, manufacturing, or biologics process development.
• Knowledge of statistics, design of experiments, and data analysis.

Responsibilities

• Lead or support daily Scale-up Lab operations, including bioreactor filling and harvesting, inoculation, sampling, feeding, operating chromatographic and filtration skids, buffer preparation, and run monitoring and troubleshooting.
• Prepare and review technical documents, including campaign summary reports and batch records.
• Participate in cross-functional teams supporting process investigations, process development, scale-up, and technology transfer to clinical and commercial manufacturing.
• Introduce, evaluate, and implement new process technologies and capabilities.
• Identify and implement process-transfer improvement initiatives with internal stakeholders.
• Support GMP-related activities for BD External Manufacturing programs as needed.
• Maintain a safe work environment in the Scale-up Lab.
• Work with an operational excellence mindset.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings, subject to plan terms and eligibility.
• Eligible U.S.-based exempt employees receive Flexible Time Off without a set accrual limit, subject to manager approval, and 11 paid company holidays each year.
• Eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires, subject to manager approval, 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, additional time-off benefits may include paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Additional discretionary incentive cash and stock opportunities may be available.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior