Senior Scientist
About The Position
Waters Corporation is seeking a scientific leader to oversee antibody and resin production supporting the VICAM® column production value stream. The role works closely with Research & Development, Engineering, and Manufacturing to ensure reliable, on-time production of antibodies and resins that meet quality, capacity, and operational requirements. The successful candidate drives process excellence, optimizes production performance, and maintains a consistent supply of key materials for customer demand and the column production line. The position includes mammalian cell culture operations, seed train expansion, bioreactor setup and operation, cryopreservation and cell banking, and accurate documentation in accordance with established procedures and safety requirements.
Requirements
- Bachelor’s degree in Cell Biology, Molecular Biology, Bioengineering, Biotechnology, or a related discipline.
- Extensive research and development experience in cell culture, cell line development, or bioprocess engineering.
- Industry experience in biologics, cell therapy, or related manufacturing environments.
- Aseptic technique and sterile handling.
- Mammalian cell culture fundamentals.
- Laboratory safety and biosafety practices.
- Basic bioreactor operations.
- Microscopy and culture assessment.
- Accurate record keeping and documentation.
- SAP ERP Systems.
Nice To Haves
- Master’s degree preferred.
Responsibilities
- Retrieve, thaw, and initiate mammalian cell lines from cryogenic storage.
- Monitor culture health, morphology, viability, and contamination status.
- Perform routine passaging and expansion of cell cultures.
- Maintain safety-stock cultures and frozen cell banks.
- Perform sterile manipulations within biosafety cabinets.
- Expand cultures through multiple vessel scales to generate inoculum.
- Evaluate expansion readiness based on growth phase and culture condition.
- Perform aseptic transfers, media additions, and feeding activities.
- Maintain proper labeling and tracking of cultures.
- Install and prepare single-use cultureware systems.
- Perform system pressurization testing and leak checks.
- Execute fill, flush, and priming procedures.
- Perform bioreactor inoculation activities.
- Monitor process parameters including temperature, pH, dissolved oxygen, and gas supply.
- Collect in-process samples for routine analysis.
- Harvest cultures for long-term storage.
- Prepare freezing suspensions using appropriate cryoprotectants.
- Aliquot into cryovials and perform controlled freezing steps.
- Maintain cryogenic storage inventory and records.
- Maintain accurate batch records and laboratory documentation.
- Record culture observations, process steps, and test results.
- Follow established SOPs and aseptic handling procedures.
- Adhere to safety and biosafety requirements.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
