Senior Scientist

ImmunEdge • Redwood City, CA

9d • $154,000 - $170,000

About The Position

ImmunEdge has an exciting opportunity for a Senior Scientist with strong in vivo pharmacology, flow cytometry, and cancer immunology experience to join our In Vivo Pharmacology team. This individual will play a key role in advancing preclinical oncology and immunology programs by designing, executing, and analyzing in vivo studies and mechanistic ex vivo assays to support target validation, candidate selection, and translational strategy. Strong candidates will be highly collaborative, scientifically rigorous, and passionate about drug discovery and immune-mediated diseases. Experience working in a dynamic, early-stage biotech environment and contributing across discovery workflows is highly valued.

Requirements

• Ph.D. in Immunology, Pharmacology, Oncology, Molecular and Cellular Biology, or a related field; or M.S. with additional relevant industry experience
• 5+ years of industry experience in drug discovery or development, with significant hands-on experience in in vivo models
• Strong technical expertise in: In vivo pharmacology and disease models (oncology and/or immunology preferred), Flow cytometry (panel design, immune phenotyping, functional assays, data analysis), MSD, ELISA, and ex-vivo-based functional assays
• Experience integrating in vivo and ex vivo data to support mechanism of action and translational hypotheses
• Proficiency with standard laboratory techniques such as ELISA, qPCR, western blotting, and cytokine assays
• Ability to independently plan and execute experiments, troubleshoot complex problems, and rigorously interpret scientific data
• Strong collaboration, communication, technical writing, and organizational skills
• Ability to thrive in a fast-paced, supportive start-up environment

Nice To Haves

• Experience with PK/PD or bioanalytical assays
• Experience writing technical reports for IND-enabling studies
• Familiarity with immuno-oncology targets or immune-modulating therapeutics
• Prior CRO management or cross-functional project experience

Responsibilities

• Design, execute, and interpret in vivo efficacy, PK/PD, and mechanistic studies in relevant oncology and immunology models
• Develop and optimize ex-vivo assays, including MSD, ELISA, RNAseq, and functional readouts to support target biology and mechanism of action
• Perform and analyze multi-parameter flow cytometry experiments, including panel design, staining optimization, acquisition, and advanced data analysis to characterize immune and tumor cell populations
• Collaborate with discovery, translational, and biomarker teams to integrate in vivo and ex vivo data and guide program strategy
• Analyze complex datasets and communicate findings clearly to cross-functional stakeholders with diverse scientific backgrounds
• Contribute to study planning, experimental timelines, and data-driven decision making for program advancement
• Maintain accurate, well-organized experimental records while ensuring a safe, compliant, and reproducible lab environment
• Identify opportunities to improve in vivo and ex vivo assay platforms and evaluate emerging technologies relevant to ImmunEdge’s pipeline

Benefits

• annual bonus plan
• equity
• comprehensive health (medical, dental, and vision) insurance for our employees and their families
• a 401k plan
• FSA plans (medical, dependent)
• an Employee Assistance Plan
• a holiday and paid time off plan

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree