Senior Scientist, Toxicology

Merck • Upper Gwynedd Township, PA

6d • $106,200 - $167,200

About The Position

The Nonclinical Drug Safety department is seeking a toxicologist to conduct and/or monitor GLP and non-GLP toxicity studies as a Study Director or Study Monitor. Toxicologists are members and leaders of collaborative, cross-functional scientific teams, addressing challenges from early discovery through late development. The role provides scientific leadership in designing and conducting in vivo studies and integrating findings from contributing scientists into reports that characterize drug candidates’ safety profiles. The successful candidate will also be interested in developing toward a broader strategic Nonclinical Drug Safety role, potentially as the nonclinical safety lead on discovery or clinical development programs.

Requirements

• PhD in toxicology, pharmacology, pharmaceutical sciences, or a related scientific discipline.
• Strong interest in collaborating with cross-functional teams and communicating openly and often with colleagues.
• Strong listening and leadership skills.
• Ability to communicate clearly verbally and in writing, including through presentations.

Nice To Haves

• GLP Study Director experience.
• Familiarity with outsourced study monitoring.
• Demonstrated understanding of Good Laboratory Practices (US FDA 21 CFR Part 58).
• Familiarity with ICH safety guidelines.

Responsibilities

• Serve as the single point of control (Study Director) for assigned acute through chronic general toxicology studies across all modalities.
• Work with technical, veterinary, and scientific staff to ensure studies comply with protocols and amendments, Standard Operating Procedures, regulations, safety guidelines, and company policies and procedures.
• Critically analyze and interpret data, integrating findings from areas such as clinical pathology, pathology, and toxicokinetics into written reports used for regulatory submissions.
• Communicate study results within established timelines.
• Ensure regulatory rigor, proactively identify risks, and support timely study execution.
• Build collaborative relationships, influence without authority, and contribute to an inclusive team environment.
• Deliver high-quality results with accountability and agility, translate objectives into action, continuously improve, embrace change, and demonstrate leadership.
• As needed, lead or participate in method development, inter-group initiatives, and related scientific projects.

Benefits

• Medical, dental, and vision healthcare and other insurance benefits for employees and their families.
• Retirement benefits, including 401(k).
• Paid holidays.
• Vacation.
• Compassionate and sick days.
• Eligible for annual bonus and long-term incentive, if applicable.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree