Senior Scientist, Target Discovery & Biology - Functional Genomics

AmgenSouth San Francisco, CA
$123,053 - $166,483

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. In this vital role you will join the Target Discovery & Biology team in South San Francisco. This role will leverage functional genomics in disease-relevant systems, including complex biological models from in vitro to in vivo, to advance target discovery and validation across Amgen’s therapeutic areas.

Requirements

  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc scientific experience in Target Discovery & Biology]
  • OR Master’s degree and 3 years of relevant scientific experience in Target Discovery & Biology
  • OR Bachelor’s degree and 5 years of relevant scientific experience in Target Discovery & Biology

Nice To Haves

  • Strong experience in molecular biology and cell engineering. Experience in complex and co-culture in vitro models is a major plus
  • Experience in executing large scale, complex, and/or in vivo genetic screens (particularly CRISPR-based) and follow up validation studies. Track record of pushing the envelope on scale and technical feasibility is highly desirable
  • Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights
  • Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment
  • Additional experience relevant to applying functional genomics approaches to new target discovery across diverse indications
  • Track record of scientific productivity and innovation as demonstrated through career experiences, project outcomes and/or publications
  • Track record of taking on new areas of research and biology with successful outcomes

Responsibilities

  • Leverage functional genomics approaches across therapeutic areas to discover novel targets and address key biological questions
  • Lead, support and execute projects from inception through target identification, validation and mechanism-of-action studies
  • Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen’s pipeline

Benefits

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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