Senior Scientist – Research Computational Biology (ARIA)

Amgen • Boston, MA

1d

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist – Research Computational Biology (ARIA) What you will do Let’s do this. Let’s change the world. The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role, you will apply your expertise in data science and mechanistic disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets within a dynamic, cross-functional research environment. Focus areas include: Deriving biological insight from complex multi-modal omics and perturbation screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses. Conducting innovative, collaborative research in close partnership with Amgen therapeutic area scientists and our Discovery Sciences, Advanced Technologies, and AI (DATA) team, spanning discovery platforms, internal pipeline programs, and external partnerships. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.

Requirements

• PhD in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable] OR Master’s degree in computational biology, bioinformatics, data science, or a related discipline and 3 years of relevant research experience OR Bachelor’s degree in computational biology, bioinformatics, data science, or a related discipline and 5 years of relevant research experience

Nice To Haves

• Strong background in cardiometabolic disease and/or immunology, including applications in the interpretation of single-cell data.
• Proficient in extracting actionable mechanistic insights from complex biological datasets through development and creative application of AI/ML-based analytical strategies.
• Strong programming skills (Python, R, Linux/Unix) and experience with cloud computing environments, HPC, and collaborative coding practices (e.g., Git).
• Track record of designing and executing creative and holistic computational strategies to address challenging research questions.
• Proven expertise in the analysis and interpretation of single-cell omics data.
• Excellent communication and presentation skills, with the ability to convey complex concepts to diverse audiences.
• Self-motivated, collaborative, and committed to continuous learning and growth.

Responsibilities

• Deriving biological insight from complex multi-modal omics and perturbation screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses.
• Conducting innovative, collaborative research in close partnership with Amgen therapeutic area scientists and our Discovery Sciences, Advanced Technologies, and AI (DATA) team, spanning discovery platforms, internal pipeline programs, and external partnerships.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees