Senior Scientist, Membrane Protein Biochemistry
About The Position
Join Amgen’s Mission of Serving Patients. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. In this vital role you will be part of an innovative integrative Protein Generation group within Discovery Protein Science, with responsibilities including (but not limited to) the design of strategies for recombinant production of polytopic membrane protein (MP) targets and their purification with detailed analytical characterization. This role will also include opportunities to develop MP platforms and capabilities that increase the success rates of large-molecule and small-molecule therapeutic discovery programs.
Requirements
- Doctorate degree PhD OR PharmD OR MD [and relevant post-doc experience] OR Master’s degree and 3 years of relevant laboratory experience OR Bachelor’s degree and 5 years of relevant laboratory experience
- Ph.D. plus relevant postdoctoral experience
- Flexible problem-solving skills, as exemplified by a consistent track record of scientific accomplishments (e.g., peer-reviewed publications and/or patents)
- Proven expertise with ÄKTA systems and analytical methods for membrane protein characterization using quality-focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry.
- Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams in a fast-paced environment
Nice To Haves
- Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus
Responsibilities
- Independently devise and implement state-of-the-art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables
- Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds
- Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward
- Keeping current in membrane protein expertise
- Advising supervisors and colleagues to shape future membrane protein technology development strategies
- Mentoring junior scientists and technical staff
Benefits
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
