Senior Scientist - Mass Spectrometry

BioIVT•Santa Clara, CA

2d•Onsite

About The Position

BioIVT is a leading global provider of research models and value-added research services for drug discovery and development. We specialize in control and disease-state biospecimens, including human and animal tissues, cell products, blood and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research, aiming to improve patient outcomes by coupling comprehensive clinical data with donor samples. As the premier supplier of hepatic products, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and their effects on disease processes. By combining our technical expertise, exceptional customer service and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in elevating science. The Senior Scientist serves as a lead scientist and analytical subject matter expert specializing in LCMS and HRMS systems. This role is responsible for independently operating and troubleshooting complex instrumentation, developing and validating analytical methods, and providing technical oversight for research and development projects. The position works cross-functionally to support complex studies, communicates scientific concepts and results, and ensures compliance with regulatory and quality standards. Additional responsibilities include maintaining laboratory equipment, developing and reviewing SOPs, preparing technical reports and client proposals, and coordinating with vendors to resolve issues. The incumbent will be expected to: Independently operate and troubleshoot LCMS and HRMS systems, proving advance support for method performance, instrumentation and study execution issues. Process and review analytical data from both scientific and regulatory perspectives. Lead the development, optimization and validation of analytical methods and procedures, including new LCMS methodologies. Provide technical oversight for research and development projects, identifying requirements and implementing new approaches. Serve as lead scientist / analytical subject matter expert on complex studies, working cross-functionally with stakeholders. Communicate scientific concepts and results through presentations, reports and training sessions. Develop, review, and maintain SOPs and provide guidance on analytical procedures, validation protocols, study plans, reports and investigations, and audits. Ensure proper maintenance and calibration of laboratories and equipment, troubleshoot instrument issues and coordinate with vendors to resolve problems. Maintain accurate logs, records, and study notebooks in compliance with regulatory and quality standards. Prepare or assist in preparing client proposals, protocols and reports requiring specialized scientific knowledge with minimal supervision. Other duties as assigned This job description is not intended to be all-inclusive. Employee may perform other related duties as required to meet our on-going needs.

Requirements

Ph.D. in Analytical Chemistry, Biochemistry, Biophysics, Pharmaceutical Sciences, or related scientific field with minimum 4 years relevant industry experience, or Master’s degree in a related scientific discipline with minimum 5–8 years relevant industry experience, or Bachelor’s degree in a related scientific discipline with minimum 8–15 years relevant industry experience; or equivalent combination of education and experience.
Demonstrated expertise in LCMS operation, troubleshoot and data interpretation, including experience operating and maintaining laboratory instrumentation such as centrifuges, spectrophotometers, incubators, balances, pH meters, HPLC systems and mass spectrometry systems required.

Nice To Haves

Proficiency in a variety of computer software programs including MS Office
Ability to work in a team laboratory environment with knowledge or familiarity with scientific terminology.
Must understand basic techniques and equipment in the laboratory.
Experience with a variety of techniques including (but not limited to) enzyme assays, spectrophotometry, and fluorimetry
Experience with the proper use, tracking and disposal of radioactive materials

Responsibilities

Independently operate and troubleshoot LCMS and HRMS systems, proving advance support for method performance, instrumentation and study execution issues.
Process and review analytical data from both scientific and regulatory perspectives.
Lead the development, optimization and validation of analytical methods and procedures, including new LCMS methodologies.
Provide technical oversight for research and development projects, identifying requirements and implementing new approaches.
Serve as lead scientist / analytical subject matter expert on complex studies, working cross-functionally with stakeholders.
Communicate scientific concepts and results through presentations, reports and training sessions.
Develop, review, and maintain SOPs and provide guidance on analytical procedures, validation protocols, study plans, reports and investigations, and audits.
Ensure proper maintenance and calibration of laboratories and equipment, troubleshoot instrument issues and coordinate with vendors to resolve problems.
Maintain accurate logs, records, and study notebooks in compliance with regulatory and quality standards.
Prepare or assist in preparing client proposals, protocols and reports requiring specialized scientific knowledge with minimal supervision.