Senior Scientist II
About The Position
AbbVie is seeking a highly motivated and experienced scientist for a role in the Analytical Development Department at AbbVie Bioresearch Center in Worcester, Massachusetts. The department develops, qualifies, and executes analytical methods and characterization studies to support product and process understanding across AbbVie’s biopharmaceutical pipeline, from discovery through commercial stages. The successful candidate will join the Process Analytics team and support development of preclinical and clinical biologic products. The role involves developing and executing separation methods, including HPLC and capillary electrophoresis, and other analytical methods to support CMC development of early-phase products and processes throughout the drug development lifecycle. The position may also mentor or supervise one or more team members, represent Analytical Development on cross-functional teams, lead development of analytical control strategies, and contribute technical reports and regulatory submissions.
Requirements
- PhD with 0–4+ years of experience, or MS with 10+ years of experience, in biochemistry, chemical engineering, analytical chemistry, pharmaceutical science, or a related discipline, in industry or academia.
- Thorough theoretical and practical understanding of the candidate’s scientific discipline.
- Effective writing and communication skills for research or regulatory materials.
- Strong written and verbal communication skills.
Nice To Haves
- Ability to work effectively cross-functionally and anticipate and respond to overall program development needs.
- Demonstrated independent thought, creativity, and scientific accomplishment.
- Self-motivation and the ability to act with urgency and passion.
- Ability to make thoughtful, integrated, timely, and meaningful recommendations or decisions and take corresponding actions.
- Experience with CMC analytical development of monoclonal antibodies or related biotherapeutic proteins.
Responsibilities
- Independently develop and apply capillary electrophoresis, HPLC separation, and other analytical methods to enable biological process development.
- Develop, qualify, and transfer fit-for-purpose in-process control methods to QC.
- Provide technical support for QC testing at internal and external GMP testing laboratories.
- Resolve project hurdles and assumptions using available information and technical expertise.
- Publish research in peer-reviewed journals and present work at scientific conferences.
- Seek out relevant literature and incorporate new information into individual projects and broader programs.
- Pursue project-relevant leads aligned with the group’s strategy.
- Maintain a high level of laboratory productivity.
- Follow corporate standards for conduct, safety, material handling, controlled drugs and radioactive compounds, GxP compliance, and animal care where applicable.
- Mentor or supervise team members as applicable, and guide and evaluate their performance.
- Represent the analytical function on CMC program teams and serve as an Analytical Development subject matter expert on cross-functional teams.
- Lead development of analytical control strategies for biologic programs.
- Plan and author internal technical reports and relevant CMC sections of regulatory submissions, including INDs and CTDs.
- Identify and lead analytical innovations that advance the group’s scientific capabilities.
Benefits
- Paid time off, including vacation, holidays, and sick leave.
- Medical insurance.
- Dental insurance.
- Vision insurance.
- 401(k).
- Eligibility to participate in long-term incentive programs.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
