Senior Scientist II, Translational Biomarkers

Arrowhead PharmaceuticalsMadison, WI
$125,000 - $140,000

About The Position

This Senior Scientist will be part of a team responsible for delivery of translational biomarker strategies for drug development candidates. The ideal candidate will possess in-depth experience in translational research/medicine and clinical biomarkers in drug development. The candidate will also have strong communication skills, ability to work in a matrixed-based, fast paced environment, solid problem-solving abilities, and a commitment to excellence.

Requirements

  • PhD in Biology or Chemistry related sciences and at least 5 or more years of industrial experience applying translational biomarker technologies for discovery and/or clinical research.
  • Extensive experience in assay development, GCLP validation, and implementation of soluble biomarker assays for clinical studies.
  • Extensive experience and thorough understanding of immunochemical techniques, protein biochemistry, LC-MS, molecular biology techniques.
  • Excellent organizational skills and familiarity with a fast-paced work environment.
  • Candidates must have current, valid authorization to work in the country where this role is located.

Nice To Haves

  • Experience with assay development for MSD, Quanterix, ELISA, NuLISA, LC-MS, qPCR platforms/techniques

Responsibilities

  • Design, develop, and execute robust “fit-for-purpose” clinical biomarker assays to support the evaluation of pharmacodynamics, and prediction of clinical response.
  • Identify and evaluate new technologies to support our evolving translational biomarker strategies.
  • Partner with outsourcing functions to evaluate new CROs, drive transitioning and monitoring internally developed assays to external vendors.
  • Effectively collaborate in a highly matrixed organization to drive advancement of early-stage projects into translational and clinical development.
  • May lead Associate Scientists as a manager or mentor.
  • Author and oversee documentation through all stages in GCLP-regulated clinical sample testing.

Benefits

  • competitive salaries
  • excellent benefit package

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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