Senior Scientist I

AbbVie•Worcester, MA

7h•$96,500 - $183,500

About The Position

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Conceive and implement novel experimental approaches to answer scientific questions. Investigate, identify, develop, and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines.

Requirements

Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
Possess thorough theoretical and practical understanding of own scientific discipline

Nice To Haves

Preferred 1+ years of industry experience in mRNA and tLNP process development.
Prior exposure to scale-up and GMP manufacturing is a plus.

Responsibilities

Experience in mRNA/dsRNA purification process development, including chromatography, TFF, and associated downstream unit operations.
Experience in tLNP formulation and purification process development, including optimization of process parameters to improve product quality attributes, robustness, and reproducibility.
Experience supporting process scale-up from bench-scale development to pilot-scale and GMP manufacturing
Routinely demonstrate scientific initiative and creativity in research or development activities.
Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
Formulate conclusions and design follow-on experiments based on multidisciplinary data.
May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
A primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
Demonstrates high proficiency across a wide range of relevant technologies.
Maintain a high level of productivity in the lab and/or pilot plant.
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.
Direct mentorship of others