Senior Scientist I, Method Development

Pharmaron • Germantown, MD

46d • $95,000 - $115,000 • Onsite

About The Position

The Senior Scientist, Method Development is responsible for leading the design, execution, and interpretation of bioanalytical large molecule assay development studies in support of preclinical and clinical programs. This role works hands-on at the bench, collaborates closely with internal stakeholders and sponsors, and helps ensure methods are scientifically sound, fit for purpose, and aligned with project timelines and regulatory expectations.

Requirements

• PhD in a scientific discipline with 5–6 years of experience in regulated large molecule bioanalytical environments, including 3–4 years of independent method development leadership.
• Master's degree with 6–7 years of relevant experience, including 4–5 years of independent method development leadership.
• Bachelor's degree with 7–8 years of relevant experience, including at least 5-6 years in a regulated environment supporting large molecule drug development.
• Demonstrated ability to develop robust, plate based and cell based, fit-for-purpose bioanalytical methods (PK, ADA and Biomarkers) for modalities such as monoclonal antibodies, bi-specifics, ADCs, ASOs, and peptides.
• Extensive experience using multiple established LBA platforms (e.g., Spectrophotometer, MSD, Revitty Alpha Lisa, Gyros, or similar established assay platforms).
• Strong written and verbal communication skills.
• Experience leading client discussions and managing multiple priorities effectively.
• Proficiency in Microsoft Excel, Word, PowerPoint, and standard laboratory calculations.

Nice To Haves

• Hands-on experience with FLOW and PCR based platforms is an added plus.
• Experience with SoftMax and Watson LIMS preferred.

Responsibilities

• Lead day-to-day method development activities for assigned preclinical and clinical programs.
• Design, execute, analyze, and document experiments in accordance with SOPs, regulatory expectations, and project needs.
• Serve as a technical contact for sponsors and internal teams, including routine study updates and scientific discussions.
• Support proposal development, scoping, and quote preparation with the Director and Business Development team, when necessary.
• Review, interpret, and present study data clearly to internal and external stakeholders.
• Provide scientific oversight, guidance, and mentoring to junior laboratory staff.
• Troubleshoot experimental issues and support refinement of methods through development and validation stages.
• Contribute scientific visibility through conference attendance, presentations, posters, or publications when appropriate.
• Perform other related duties as assigned.

Benefits

• Insurance including Medical, Dental & Vision with significant employer contributions
• Employer-funded Health Reimbursement Account
• Healthcare & Dependent Care Flexible Spending Accounts
• 100% Employer-paid Employee Life and AD&D Insurance, Short- and Long-Term Disability Insurance
• 401k plan with generous employer match
• Access to an Employee Assistance Program

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree