Senior Scientist, Discovery Pharmaceutical Sciences (On-site)

Merck•Upper Gwynedd Township, PA

4d•$117,000 - $184,200•Onsite

About The Position

The Discovery Pharmaceutical Science (DPS) group based in West Point, PA is seeking a Senior Scientist. DPS is a multi-disciplinary research group that provides drug delivery, solid state, solution chemistry, and formulation tools in Drug Discovery and Early Drug Product Development. In this dynamic role, your support will guide our multi-disciplinary drug discovery efforts in the therapeutic areas at our West Point site. You will closely interact with other key functions required for the progression of clinical candidate selection including Safety Assessment, Process Research, Analytical Chemistry, Drug Metabolism and Pharmacokinetics and Vaccines.

Requirements

Minimum of a bachelor’s degree with a minimum of 5 years relevant experience OR a master's degree with a minimum of 3 years relevant experience OR a PhD with less than 1 year of relevant experience.
Excellent verbal and written communication skills are required.
Strong leadership/interpersonal skills and a desire to work in a team environment with cross-functional interactions are also essential.
Automation
Automation Tools
Biotherapeutics
Cross-Functional Teamwork
Data Analysis
Design Automation
Drug Delivery Technology
Drug Formulations
High-Throughput Screening
Pharmacodynamics
Pharmacokinetics
Preclinical Research
Preformulation
Protein Purifications
Vaccine Development

Nice To Haves

Candidates with experience in pre-clinical / clinical formulation development, physico-chemical characterization, executing and troubleshooting automated workflows across a wide range of modalities are strongly preferred.
Candidates with specific experience in vaccines development, delivery of novel modalities and design of experiments, are also preferred.

Responsibilities

Design and conduct high-throughput automated experiments for pre-clinical characterization that support structural property relationships and design for delivery.
Create and deploy novel automation capabilities to drive continuous improvements in operational efficiency, miniaturization, predictive sciences and machine learning.
Tackle scientific challenges related to physical/biophysical and chemical/biochemical stability of drug candidates and enhancing bio-performance with enabled formulation strategies.
Identify suitable oral and parenteral preclinical formulations for pharmacology and toxicology studies across a variety of administration routes and modalities (small molecules, peptides, proteins, vaccines, and biotherapeutics).