Senior Scientist - Computational Materials Science
About The Position
Pfizer’s purpose is to deliver breakthroughs that change patients' lives, and at the heart of this mission is our Research and Development team. We are dedicated to translating advanced science and innovative technologies into the therapies and vaccines that matter most. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities. Our goal is to accelerate the delivery of best-in-class medicines to patients around the globe, making a significant impact on global health. The Computational Materials Science Scientist will apply state-of-the-art computational chemistry and crystallographic tools to predict the solid-state and particle properties of Pfizer molecules to streamline experimental efforts and to design better medicines. This will enable Pfizer project teams to de-risk their programs and to move rapidly into clinical studies with the goal of commercialization. The role is highly collaborative, requiring extensive work on multi-disciplinary project teams. With this role there is also a significant opportunity to publish peer reviewed research and to develop novel computational methods, addressing gaps in our current knowledge and capabilities.
Requirements
- Candidate to have a PhD in Computational Chemistry, Physics, Materials Science or Engineering, or a closely-related discipline; OR a Master’s degree in these disciplines with 5-10 years of relevant experience in industry or academia. This is an individual contributor role.
- Strong coding skills in a scientific programming language (such as C/C++, Python, Perl) with demonstrated evidence of coding expertise and data analysis.
- Competency in UNIX/Linux and HPC environments for submission and monitoring of jobs.
- Permanent work authorization in the United States.
Nice To Haves
- Experience with computational chemistry software (GROMACS, Gaussian, GAMESS-US, cp2k, quantum espresso and VASP) and the CCDC tools preferred.
- Knowledgeable of fundamental physical chemistry and materials science concepts such as thermodynamics, solvation, crystallography, symmetry, nucleation and crystal growth — either through coursework or experience.
- Strong analytical and mathematical skills (geometry, algebra, statistics, differential calculus).
Responsibilities
- Apply state-of-the-art physics based computational approaches to predict the properties and performance across range of molecules (R05 and bR05)
- Conduct crystal structure prediction (CSP) calculations and free energy calculations for polymorph stability ranking
- Utilize various physics/informatics (i.e. molecular simulations, density functional theory, H-bonding propensity analysis, full Interaction map) based computational tools for design and derisking of commercial solid form
- Develop and apply physics/ML-AI based computational tools to investigate and understand the particle properties, surface and performance
- Participate on multidisciplinary project teams and collaborate with colleagues to define and recommend follow up screening and characterization strategies to complement computational studies according to project timelines.
- Oversee the work of external partners conducting computational analyses and provide tactical guidance and critical analysis of their work
- Solve scientific problems using contemporary solid state computational techniques.
- Lead the development of new scientific approaches and knowledge within the Material Sciences organization. This is an individual contributor role.
Benefits
- 401(k) plan with Pfizer Matching Contributions
- additional Pfizer Retirement Savings Contribution
- paid vacation
- holiday and personal days
- paid caregiver/parental and medical leave
- health benefits to include medical, prescription drug, dental and vision coverage.
- Relocation support available
- Relocation assistance may be available based on business needs and/or eligibility.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
