Senior Scientist, Assay Development & Screening

Novartis

6d • Onsite

About The Position

We are seeking a highly motivated and experienced Senior Research Scientist to join our dynamic team in La Jolla, CA. The ideal candidate will work on-site full time and bring deep expertise in assay development and high-throughput screening, with experience in automated screening. If you have a passion for advancing scientific discovery and thrive in a fast-paced, collaborative and cross-disciplinary environment, we encourage you to apply.

Requirements

• BS or MS (preferred) degree in a relevant scientific discipline (e.g., Biochemistry, Molecular Biology, Cell Biology, Oncology, Neurosciences, or a related field), with 4+ years industry experience in assay development and high-throughput screening.
• Ability to manage multiple projects independently and adapt to evolving research priorities.
• Demonstrated proficiency in validating and troubleshooting biochemical and cell-based assays.
• Strong analytical, troubleshooting, and problem-solving skills.
• Excellent communication and teamwork abilities.

Nice To Haves

• Experience and initiative to integrate novel or emerging technologies into screening workflows.
• Familiarity with data analysis software and electronic laboratory management systems.
• Hands-on experience with laboratory automation platforms and liquid handling systems.
• Experience with biophysical assays or label-free target engagement approaches.

Responsibilities

• Execute routine assays on a weekly basis for defining structure-activity relationships.
• Design, develop, and optimize biochemical and cell-based assays tailored for screening in high-density formats.
• Implement and manage automation solutions to enhance assay throughput and data quality.
• Collaborate with cross-functional teams to integrate new technologies and workflows into ongoing research projects.
• Analyze, interpret, and present scientific data to internal and external stakeholders.
• Maintain detailed laboratory records, contribute to the preparation of research reports and publications, and represent the team through internal presentations.

Benefits

• US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
• In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees