Senior Scientist, Analytical Genomics

Novartis • Cambridge, MA

11d • $93,800 - $174,200 • Onsite

About The Position

We are seeking a highly skilled and motivated scientist to join our laboratory, specializing in NGS and in advanced spatial and single-cell genomics. The successful candidate will be responsible for the planning, execution, and optimization of experiments using spatial transcriptomics and single-cell protocols and instrumentation. This role is pivotal for supporting research projects, driving innovation, and ensuring high-quality data generation. Internal Job Title: Senior Scientist I Position Location: Cambridge, MA, onsite Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you. #LI-Onsite About Our Laboratory: Our lab is dedicated to advancing drug discovery at Novartis Biomedical Research with cutting-edge sequencing and genomics technologies. We strive to deliver impactful scientific discoveries, foster a collaborative work environment, and, importantly, love what we do.

Requirements

• BS or MS in Molecular Biology, Genomics, Biochemistry, or a related field, with 4+ years of hands-on experience with spatial transcriptomics and/or single-cell sequencing technologies.
• This is not a PhD level position.
• Strong understanding of molecular biology techniques like PCR, qRT-PCR, enzymatic reactions, DNA & RNA purification and manipulation.
• Proficiency in protocol development, troubleshooting, and optimization for complex genomics assays.
• Knowledge of NGS library preparation and sequencing workflows.

Nice To Haves

• Experience with tissue processing and imaging, IHC, microscopy.

Responsibilities

• Plan and perform experiments utilizing state-of-the art single cell and spatial profiling platforms.
• Implement and optimize protocols for sample preparation, library construction, and sequencing.
• Ensure rigorous documentation and reproducibility of all laboratory procedures.
• Operate and maintain relevant instruments, including troubleshooting and routine care.
• Train and mentor junior staff on instrument use and protocol adherence.
• Perform initial data processing for spatial and single-cell genomics datasets using appropriate bioinformatics tools.
• Collaborate with Data Scientists to interpret results, prepare reports, and present findings internally.
• Work closely with cross-functional teams, including molecular biologists, bioinformaticians, and project leaders at Novartis Biomedical Research, local and remote.
• Contribute to experimental planning and reporting.
• Document work and monitor quality control measures to ensure data integrity and compliance with laboratory standards.
• Stay current with advances in single-cell and spatial genomics technologies and integrate best practices into lab workflows.

Benefits

• health, life and disability benefits
• a 401(k) with company contribution and match
• a variety of other benefits
• a generous time off package including vacation, personal days, holidays and other leaves
• performance-based cash incentive
• eligibility to be considered for annual equity awards

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Associate degree