Senior Research Technician, Integrated Genomics Operation
About The Position
The Senior Research Technician will join Memorial Sloan Kettering Cancer Center’s Integrated Genomics Operation (IGO), a high-throughput core facility that provides genomic services and expertise to research scientists and physicians across the Cancer Center. The IGO supports basic, clinical, and translational research, generating more than 100 TB of data annually across more than 40 applications, including single-cell and spatial transcriptomics technologies. The role involves mastering a variety of genomics assays using robotics or traditional benchwork and collaborating with other IGO teams. The technician will extract and assess nucleic acids from diverse biomaterials, train on spatial transcriptomic methods, and learn droplet digital PCR theory and experimental execution. The position also includes operating automated instruments, maintaining laboratory records and billing information, communicating with vendors, and helping develop workflows using LEAN principles.
Requirements
- Bachelor’s degree in biology, chemistry, or a related field and at least 2 years of experience, or a master’s degree.
- Exceptional attention to detail and strong analytical skills.
- Ability to manage multiple projects accurately in a fast-paced research environment.
- Critical-thinking and problem-solving skills to troubleshoot experimental challenges.
- Strong interpersonal and communication skills, including the ability to interact professionally across all levels.
- Comfort with manual or automated processing.
- Enthusiasm and dedication to MSK’s vision, mission, and values.
Nice To Haves
- Previous exposure to purifying nucleic acids for NGS platforms.
- Knowledge of digital PCR.
- Experience with cells and FFPE samples.
Responsibilities
- Extract nucleic acids from varied biomaterials, including fresh-frozen and formalin-fixed paraffin-embedded tissue, cell lines, blood, plasma, serum, saliva, and nails.
- Perform quality assurance and quality control on extracted material.
- Train on spatial transcriptomic methods using 10x Genomics platforms.
- Learn the theory, design, and execution of droplet digital PCR experiments used to validate oncogenic alterations.
- Work with the team to create a workflow following LEAN principles.
- Communicate with vendor technical support and sales representatives.
- Operate liquid handlers and robotic instruments for high-throughput processing.
- Maintain accurate and detailed records in the Examplar Sapio Laboratory Information Management System (LIMS).
- Use iLAB for billing purposes.
- Interface with other teams within the Integrated Genomics Operation.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
