Senior Research Associate

Cytokinetics•South San Francisco, CA

1d•Onsite

About The Position

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. At Cytokinetics, each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious, compassionate, and collaborative individuals who are driven to make a positive impact. We seek a highly motivated Senior Research Associate to support our preclinical cardiac research programs with expertise in cardiomyocyte maintenance and differentiation. As a senior research associate, you will conduct and manage experiments to evaluate the efficacy of novel small molecule compounds in the treatment of cardiac and skeletal muscle diseases. This role requires a proactive individual who can collaborate within a multidisciplinary team and contribute to advancing compounds through preclinical research and development.

Requirements

BS/MS in Biology, Physiology, Pharmacology, or a related field with 3-5 years of relevant research experience.
Ability to work weekends, as needed, for iPSC maintenance and experimental timepoints
Basic data management skills and the ability to present data clearly and effectively is required.
iPSC culture experience required with a preference for individuals with cardiomyocyte differentiation experience.
Prior experience in a range of biochemical and molecular biology techniques (e.g. flow cytometry, western blots, qPCR, immunohistochemistry, etc) is preferred.
Team-oriented, detail-oriented, proactive.
Excellent oral and written communication skills are essential

Nice To Haves

Experience in a pharmaceutical/biotechnology environment is a plus.

Responsibilities

Establish and maintain iPSC banks with diverse genetic backgrounds, including routine quality control and line characterization
Maintain various iPSC lines in culture and perform cardiomyocyte differentiation and characterization
Conduct both cellular and biochemical assays to support preclinical drug discovery programs in cardiac muscle biology.
Measure biomarkers of disease progression and compound efficacy.
Document experimental methods and results, manage data, and present research findings.
Collaborate closely with other team members to build understanding of cardiovascular disease pathogenesis and the mechanism of action of drug candidates.