Senior Research Associate – Protein Therapeutics

Gilead Sciences•Foster City, CA

About The Position

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. Protein Therapeutics in Gilead Research has an exciting opportunity for a Senior Research Associate to join the Protein Sciences team. The successful candidate will be a highly motivated scientist with hands-on knowledge in recombinant antibody purification and protein analytics. The candidate will demonstrate the ability to produce and interpret experimental data with scientific rigor and independence. With guidance from the manager, the individual will work effectively with cross-functional project teams to generate and validate therapeutic proteins and tool molecules, including monoclonal and bispecific antibodies, immunocytokines, and other complex biologics. The ideal candidate is hard-working, team-oriented, professional, diligent, and motivated to expand his/her technical and scientific skills.

Requirements

2+ Years with BS OR 0+ Years with MS
BS in Biology, Biochemistry, Chemistry or related field with at least 2+ years of relevant experience (3+ years preferred) or MS with above listed characteristics and techniques for the position

Nice To Haves

Strong background in protein sciences and protein biochemistry
At least 2 years of direct experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and complex biologics (e.g., bi/multi-specific antibodies)
Hands-on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using AKTA Avant/Pure
Proficiency with various analytical protein characterization techniques such as SEC-HPLC or UHPLC, SDS-PAGE or CE-SDS, Endosafe
Ability to perform method development and write protocols
Strong work ethic and detailed record-keeping are required
Ability to multi-task and work in a fast-paced team environment
Familiarity with other protein characterization technologies (DLS, SEC-MALS, LC/MS, IEX/HIC-HPLC)
Operating experience with various automation instruments e.g., autosamplers, automated liquid handling systems
Training and experience in automation system programing or scripting

Responsibilities

Perform protein purification and characterization for quality and document work in electronic lab notebook and various informatics systems to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.
Prepare technical reports, summaries, and check in protein samples into the sample bank.
Use good oral and written communication skills to relay scientific data and update collaborators of purification status and challenges.
Actively participate in group meetings, present results, interpret data, draw conclusions and propose next steps for the presented work.
Maintain awareness of cutting-edge technical developments and scientific knowledge and apply these where possible to improve work quality and efficiency.