Senior Research Associate/Associate Scientist, Cell Process Development & Manufacturing

Retro•Redwood City, CA

About The Position

Retro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to broadly improve tissue function by targeting mechanisms of aging with the ultimate aim of adding 10 years to healthy human lifespan. We’re building a mission-driven team of accomplished and kind individuals who embrace our startup culture of rapid iteration, transparency, and versatility. We are hiring a new member of the Microglia Therapeutics team who will help us ramp toward manufacturing readiness. In the near term, this role will focus on hands-on execution of cell culture and manufacturing-related activities in support of GMP readiness and production. Over time, as manufacturing operations become established, this person may also contribute more broadly to process development activities.

Requirements

B.S. in Biology or a related field and at least 5 years of relevant experience, or an M.S. with at least 3 years of post-degree research experience.
Hands-on experience with mammalian cell culture, including work with bioreactors and process development activities.
Willing to do hands-on manufacturing work and can execute consistently in structured, SOP-driven environments.
Work well in a collaborative, fast-moving environment and maintain detailed, high-quality documentation.

Nice To Haves

Experience with iPSCs or microglia culture.
Worked in a GMP manufacturing facility.

Responsibilities

Perform culture of mammalian cells, mainly iPSCs using aseptic technique.
Differentiate iPSCs to brain cell types like microglia in a bioreactor.
Formulate media and reagents for PD and manufacturing activities.
Follow SOPs and perform work in a GMP facility.
Work collaboratively across Retro teams such as Manufacturing, Assay Development, Quality Control, Automation, etc.
Analyze and present experimental data to our internal teams and collaborators.
Maintain highly organized and detailed notes in an electronic lab notebook and contribute to supporting documents.
Perform regular lab organization activities and ordering.