Senior Project Manager

JLL•South San Francisco, CA

18h•Onsite

About The Position

JLL empowers individuals to shape the future of real estate by combining world-class services, advisory, and technology for clients. The company is committed to hiring talented people, empowering them to thrive, grow meaningful careers, and find a place where they belong. This position is for a Senior Project Manager responsible for the end-to-end delivery of life sciences capital projects. These projects include GxP facility renovations (minor and major), new laboratory/manufacturing builds, and critical utility infrastructure upgrades. The role ensures all projects maintain a "state of control" and meet stringent regulatory requirements.

Requirements

Bachelor’s degree in Engineering (Mechanical, Chemical, or Civil), Construction Management, Architecture, or a related scientific field
PMP (Project Management Professional) certification
7–10 years of project management experience in complex technical construction
5+ years of specific experience in Life Sciences, Biotech, or Pharmaceutical environments
Proven track record managing GMP facility capital projects ($1M–$25M+), including cleanroom build-outs (ISO 5–8), laboratory renovations, and critical infrastructure (validated HVAC, WFI/RO high-purity water, and EMS)
Expertise in overseeing the technical integration of manufacturing skids, analytical instrumentation, and specialized containment areas (e.g., BSL-2/3)
Deep understanding of FDA (21 CFR Part 211) and EMA regulatory requirements
Experience interfacing with local authorities, including zoning and specialized fire/safety code officials for hazardous material storage
Mastery of the V-Model approach, including IQ/OQ/PQ protocols and Turnover Packages (TOP)
Direct experience managing Change Controls, Deviations, and CAPAs within a regulated project lifecycle
Proficiency in MS Project or Primavera P6
Expertise in budget forecasting and mitigating "scope creep" in highly regulated environments
Ability to perform FMEA (Failure Mode and Effects Analysis) to protect product integrity during construction
In-depth knowledge of ISO 14644 standards and Grade A–D operational requirements
Understanding of unidirectional flow for personnel, material, and waste to prevent cross-contamination
Proficiency in BIM/VDC platforms (Autodesk Construction Cloud, Procore) and document control for audit-ready project files
Ability to lead teams of MEP engineers, Validation specialists, QA/QC officers, and Architects of Record
Ability to present project risks and financial health to C-suite stakeholders and Steering Committees
Skill in negotiating with specialized sub-contractors and vendors
Ability to assess if a construction delay or field change impacts the validated state of the facility
Applying "Lean Construction" or specialized methodologies to minimize downtime during facility shutdowns
Candidates must be authorized to work in the United States without sponsorship

Nice To Haves

ISPE (International Society for Pharmaceutical Engineering) membership or LEED AP certification
Experience with Brownfield projects (renovating active GMP facilities without interrupting production)
Familiarity with Digital Plant initiatives (Smart Buildings, IoT sensors for monitoring, and Lab Automation)

Responsibilities

End-to-end delivery of life sciences capital projects, including GxP facility renovations (minor and major), new laboratory/manufacturing builds, and critical utility infrastructure upgrades
Ensuring all projects maintain a "state of control" and meet stringent regulatory requirements
Managing Change Controls, Deviations, and CAPAs within a regulated project lifecycle
Budget forecasting and mitigating "scope creep" in highly regulated environments
Performing FMEA (Failure Mode and Effects Analysis) to protect product integrity during construction
Leading teams of MEP engineers, Validation specialists, QA/QC officers, and Architects of Record
Presenting project risks and financial health to C-suite stakeholders and Steering Committees
Negotiating with specialized sub-contractors and vendors (e.g., orbital welders, cleanroom panel installers)
Assessing if a construction delay or field change impacts the validated state of the facility
Applying "Lean Construction" or specialized methodologies to minimize downtime during facility shutdowns