Senior Product Manager, AI Applications

Sequencing • Iowa, DE

1d • Remote

About The Position

Sequencing is building the interface between humanity and its DNA. Using clinical-grade whole genome sequencing, AI, and a rapidly expanding ecosystem of genomic applications, we help people better understand themselves, their health, and their future through their DNA. The human genome is one of the most valuable and underutilized resources in the world. Our mission is to transform the human genome into a lifelong source of personalized guidance and build the trusted home for every genome on Earth. As the world’s largest direct-to-consumer whole genome sequencing platform, Sequencing is helping define the future of AI-powered personalized health. We’re a profitable, venture-backed, fully remote company building category-defining products that help people better understand themselves through their DNA.

Requirements

• 7 to 10 years of product management experience with a strong record shipping polished native-mobile consumer products.
• Proven ability to drive measurable improvements in activation, engagement, repeat use, retention, or subscription value.
• Strong product taste and ability to articulate why an experience earns trust, feels coherent, and creates a reason to return.
• Proficiency in using analytics, experiments, customer research, and qualitative evidence to make and revisit product decisions.
• AI-native and hands-on; ability to use AI to prototype, interrogate requirements, explore product states, and accelerate learning.
• Ability to speak concretely about the tools, evaluation, guardrails, and failure modes behind an AI-powered experience, even when not the platform owner.
• Ability to translate complex scientific or technical capabilities into clear consumer behavior without flattening important uncertainty.
• Skill in writing clear PRDs and partnering effectively with Engineering, Bioinformatics, Design, Customer Success, and platform teams.
• Based in the United States and comfortable operating autonomously in a fast-moving, fully remote environment.

Nice To Haves

• Experience in health, wellness, genomics, or another trust-sensitive consumer domain.
• Experience with conversational interfaces, longitudinal personalization, subscriptions, or lifecycle engagement.
• Experience with signed-in web experiences that extend a native-mobile product.

Responsibilities

• Own the day-to-day product roadmap for the polished, consumer-optimized experiences through which members interact with Sequencing’s intelligence layer.
• Own the signed-in member web experience as an extension of the same journey.
• Combine strong consumer-mobile judgment with hands-on AI fluency.
• Use analytics, experimentation, customer research, and Customer Success signals to turn complex genomic intelligence into experiences that feel clear, trustworthy, emotionally resonant, and increasingly valuable over time.
• Manage the day-to-day member-facing mobile roadmap and the near-term signed-in member web experience.
• Develop a coherent end-to-end member journey across onboarding, asking questions, understanding answers, memory and personalization, proactive guidance, and returning over time.
• Drive product outcomes for trust, activation, repeat use, engagement, and long-term retention.
• Translate intelligence-layer capabilities into polished product behavior, working closely with the AI Platform PM, Engineering, Bioinformatics, and Design.
• Create rapid prototypes and user tests that clarify product intent before expensive implementation.
• Establish a disciplined learning loop using analytics, experiments, user feedback, Customer Success signals, and market evidence.
• Produce clear PRDs, acceptance criteria, success measures, happy and unhappy paths, and visible unresolved decisions.
• Ensure a product experience that communicates scientific uncertainty honestly without sacrificing usefulness or confidence.

Benefits

• Comprehensive medical, dental, and vision insurance coverage
• 401(k) with company matching
• Paid time off (PTO)
• Paid volunteer time off
• Fully remote work with home office stipend
• Parental bonding leave
• Clinical-grade whole genome sequencing for you and your family (private and confidential)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: No Education Listed