Senior Principal Solutions Architect - PLM & Digital Thred

MESO SCALE DIAGNOSTICS, LLC. • Rockville, MD

3d • $151,400 - $236,600

About The Position

The Senior Principal Solutions Architect – PLM & Digital Thread serves as MSD's enterprise authority for Product Lifecycle Management (PLM), Digital Thread, Product Data Model Management, and Digital Thread initiatives. This role is responsible for defining and executing the long-term PLM and Digital Thread strategy, enterprise architecture, governance framework, and technology roadmap supporting product development, quality, manufacturing, supply chain, and regulatory operations. The Senior Principal Solutions Architect partners with executive leadership to drive enterprise-wide digital thread initiatives, establish architecture standards, influence technology decisions, and ensure alignment.

Requirements

• Bachelor’s degree in Computer Science, Engineering, or a related field.
• A minimum of 14 years of progressive experience in enterprise architecture, digital transformation, PLM, or engineering systems leadership.
• A minimum of 10 years of leading large-scale PLM implementations and business transformation initiatives.
• Seven years of hands-on experience with Siemens Teamcenter PLM, including implementation, configuration, upgrading, and administration across multiple versions and releases.
• Demonstrated experience designing integrations between PLM and downstream enterprise systems (MES and/or ERP).
• Experience implementing PLM in FDA-regulated or GxP environments, including computer system validation and 21 CFR Part 11 compliance.
• Transformational experience: demonstrated history of leading or significantly contributing to enterprise-scale PLM implementations that changed how an organization operates.
• Demonstrated success establishing enterprise architecture standards and governance frameworks.
• Proven track record as a Solutions Architect or senior PLM technical leader, with demonstrated experience implementing digital thread processes in partnership with business process owners.
• In-depth knowledge of core Teamcenter modules: Active Workspace, BMIDE, workflow design, change management, and data models.
• Expert-level knowledge of Siemens Teamcenter X and the broader Siemens digital industries ecosystem.
• Demonstrated ability to implement integration frameworks connecting PLM to MES and ERP platforms under the direction of a process owner.
• Knowledge of C#, Visual Basic, JavaScript, MSSQL, and/or XML.
• Knowledge of Agile methodologies (e.g., Scrum).
• Enterprise Architecture governance and methodology expertise.
• Deep understanding of Digital Thread and Product Data Management disciplines.
• Cloud architecture and enterprise integration platform expertise.
• Working knowledge across the majority of: Product Design & Development, Engineering, Software Design, Manufacturing, Quality, and Validation.
• Ability to explain complex technical architecture to non-technical stakeholders and executive leadership.
• Solid technical leadership with demonstrated staff management, accountability setting, and performance management capabilities.
• Excellent analytical and logical problem-solving skills with the ability to organize and drive project tasks forward in a structured fashion.
• Ability to lead enterprise-wide initiatives through influence rather than direct reporting authority.
• Strong drive to increase business value through continuous improvement.
• Excellent oral, written, and interpersonal communication skills.

Nice To Haves

• Direct experience with Teamcenter X (cloud/SaaS PLM).
• Consulting experience across multiple customers and implementations in the life sciences industry.
• Experience architecting integrations specifically with JD Edwards EnterpriseOne (JDE).
• Experience supporting ISO 9001 quality management systems.
• Experience evaluating and selecting strategic enterprise technology platforms.
• Working knowledge of MES principles and manufacturing data flows, including work order management, shop floor routing, and production traceability in both discrete and process manufacturing.
• Familiarity with digital thread concepts: Production configuration management, routers, BOM lifecycle management, document management, change management and closed-loop quality integration across enterprise systems.

Responsibilities

• Define and champion the enterprise PLM and Digital Thread vision, strategy, governance framework, and multi-year roadmap aligned with MSD's business objectives.
• Serve as a trusted advisor to executive leadership, influencing decisions related to Digital Thread, Digital Twin, product data management, and enterprise transformation initiatives.
• Establish enterprise architecture standards and identify innovative technologies that improve operational performance, accelerate product development, and support MSD's long-term growth strategy.
• Architect, configure, and implement PLM solutions in Teamcenter X to support engineering, quality, and manufacturing processes — with a focus on establishing a unified digital thread from product design through manufacturing execution and commercial operations.
• Partner with the Digital Thread Process Lead to translate defined process requirements into Teamcenter X configurations, workflows, and integrations.
• Serve as the subject matter expert on Siemens Teamcenter X: administer the platform, stay current with SaaS release cycles, and drive adoption of evolving best practices.
• Lead architecture reviews and approve solution designs impacting enterprise systems.
• Drive strategic roadmap planning for Teamcenter X and associated technology platforms.
• Design and maintain integrations between Teamcenter X, MES platforms, and JD Edwards EnterpriseOne (JDE) — ensuring data integrity and process continuity across the product lifecycle.
• Design contextually relevant MES integrations covering work order execution, shop floor routing, material tracking, and production traceability.
• Support data-flow design between ERP and PLM/MES layers, including manufacturing, procurement, quality management, and inventory modules in JDE.
• Implement and maintain integrations with CAD tools (including ECAD), laboratory systems, and other enterprise applications.
• Establish enterprise integration architecture standards across PLM, MES, ERP, QMS, LIMS, and other critical business platforms.
• Define master data governance strategies and lifecycle management standards.
• Provide ongoing operational support for Teamcenter X and its integrated systems — including incident response, break/fix resolution, user support, system health monitoring, and vendor escalation coordination.
• Troubleshoot and resolve software issues across the PLM and integration stack.
• Drive continuous improvement of the PLM platform and integration architecture in alignment with MSD’s digital transformation roadmap.
• Lead vendor governance and strategic roadmap alignment with Siemens and other technology partners.
• Establish and monitor service-level objectives, performance metrics, and operational KPIs.
• Lead architecture discussions and design technical solutions in support of business partners’ digital transformation initiatives.
• Serve as the primary technical advisor for PLM and Digital Thread initiatives across the enterprise.
• Collaborate with cross-functional teams and business/functional analysts to gather requirements, create specifications, and deliver validated solutions that meet 21 CFR Part 11 and GxP requirements.
• Mentor architects, analysts, developers, and technical leaders to build internal capability.
• Collaborate with business process owners and the project management office to define implementation plans, manage priority items, and align PLM roadmap milestones with digital transformation program objectives.
• Ensure testing is appropriate and complete, business process procedures are accurate, and all configuration and validation standards are adhered to.
• Coach team members to build internal PLM technical capability and reduce dependency on external resources.

Benefits

• Medical coverage
• Dental coverage
• Vision coverage
• Prescription benefits
• 401(k) plan with company matching
• Flexible spending accounts
• Company-paid short-term disability insurance
• Company-paid long-term disability insurance
• Group life insurance
• Accidental death and dismemberment insurance
• Paid vacation
• Paid sick leave
• Paid holidays
• Paid parental leave
• Employee assistance program
• Fitness club membership contribution
• Pet insurance
• Identity theft protection
• Home and auto insurance discounts
• Optional supplemental life insurance

What This Job Offers

• Job Type: Full-time
• Career Level: Senior