Senior Principal Scientist, Lab Head, Immunomodulation / Cell Reprogramming

Sanofi•Cambridge, MA

6d•$148,500 - $214,500•Onsite

About The Position

Sanofi Oncology is seeking a highly motivated individual with project leadership experience and deep knowledge in immuno-oncology. This individual will play a leading role in developing novel cell reprogramming and other therapies aimed at modifying the tumor microenvironment to treat cancer. The successful candidate will lead a team within the Immunomodulation & Cell Reprogramming Cluster where they are expected to support progression of existing programs, develop new projects, and contribute to the growth of the Immuno-Oncology portfolio. The position is based in Cambridge, Massachusetts, USA. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

Requirements

Ph.D. in Immunology, Immuno-Oncology, Cell Biology, Molecular Biology, or related discipline
Minimum of 7 years of post-graduate research experience in the pharmaceutical, biotechnology, or related industry
Deep knowledge in immunological mechanisms or tumor immunology
Experience in cell therapy and/or tumor microenvironment research
Hands-on experience in isolation and immune phenotyping of murine and human immune populations (e.g., cell sorting, flow cytometry), functional assessment of immune subsets (e.g., proliferation, cytotoxicity, cytokine/chemokine measurement), and murine tumor models including immune deficient and humanized mice
Familiarity with techniques for genetically modifying immune cells to express novel transgenes
Excellent organizational, communication, and presentation skills with the ability to work both collaboratively and independently

Responsibilities

Lead and manage a team of scientists and cross-functional research teams, ensuring timely progression of projects from early concepts to first-in-human studies
Mentor and develop team members, fostering scientific excellence, professional growth, and a lead-by-example culture
Develop clear scientific strategies to support departmental goals and allocate resources to drive overall group performance
Demonstrate innovation in research with deep understanding of clinical translation
Apply scientific expertise to initiate, design, direct, and execute experiments while ensuring compliance with laboratory safety and documentation protocols
Keep current with developments in basic research, clinical development, and the competitive landscape
Publish and present findings in peer-reviewed journals and scientific conferences