Senior/Principal Associate Scientist, Mammalian Physiology

Calico•South San Francisco, CA
•$130,000 - $161,000•Onsite

About The Position

Calico is seeking a Senior/Principal Associate Scientist to join an interdisciplinary, collaborative team working at the intersection of mammalian stress response pathways and disease. The role calls for a skilled experimentalist with strong critical-thinking and communication skills and a history of productivity in fast-paced work environments. The successful candidate will work independently and collaboratively and be detail-oriented, organized, adaptable, and self-motivated. The position focuses on coordinating and conducting in vivo studies, preparing and managing samples, performing downstream assays, and leading the development and execution of primary cell culture assays. The scientist will communicate experimental results and project progress in forums such as lab meetings. The role is onsite five days a week.

Requirements

  • BS or MS degree in physiology, biology, genetics, neuroscience, or a related field.
  • At least 8 years of extensive experience with in vivo mammalian model systems for candidates with a BS, or at least 6 years for candidates with an MS.
  • Proficiency in mammalian in vivo experiments and primary cell isolation and culture.
  • Experience deploying biochemical, cellular, and molecular assays, histology, and immunofluorescence.
  • Excellent written and oral communication skills.
  • Strong organizational skills and ability to multitask.
  • Ability to analyze and interpret complex data.
  • Track record of learning new skills quickly.
  • Ability to collaborate closely with different teams to achieve project goals.
  • Ability to independently plan, execute, and analyze experiments to meet time-sensitive goals.
  • Basic statistical skills.
  • Willingness to work onsite five days a week.

Nice To Haves

  • Familiarity with complex co-culture systems and/or organoids.
  • Prior experience working with data software such as Prism.

Responsibilities

  • Manage and coordinate in vivo studies in collaboration with the Research Physiology team.
  • Independently conduct smaller in vivo studies.
  • Prepare and manage samples and execute downstream assays.
  • Lead the development and execution of primary cell culture assays.
  • Communicate experimental results and project progress in forums such as lab meetings.

Benefits

  • Eligible for two annual cash bonuses.
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