Senior Oligonucleotide Chemist

Eurofins • Lancaster, PA

3h • Onsite

About The Position

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years. The Oligonucleotide Scientist is responsible for developing, optimizing, validating, and executing analytical methods to support oligonucleotide API, drug substance, and drug product testing. The role focuses primarily on HPLC/UHPLC and mass spectrometry (e.g., LC‑MS, LC‑MS/MS) for identity, purity/impurity profiling, quantitation, and stability-indicating assessments. The scientist will author methods, protocols and reports, ensure data integrity and compliance within GxP environments, and provide technical leadership for routine testing and investigations and mentoring of junior staff. Applies GMP in all areas of responsibility, as appropriate.

Requirements

• Authorization to work in the U.S. indefinitely without restriction or sponsorship
• BS or MS degree in analytical chemistry or other related degree concentration
• BS and 4+ years of industry experience, MS and 2+ years of industry experience, or PhD and 1+ year of industry experience
• Industry experience with oligonucleotides and drug product testing
• 3-5 years of experience with LC chromatographic validation in a GMP environment

Nice To Haves

• Excellent communication (oral and written) and attention to detail
• Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies

Responsibilities

• Developing, optimizing, validating, and executing analytical methods to support oligonucleotide API, drug substance, and drug product testing
• Focusing primarily on HPLC/UHPLC and mass spectrometry (e.g., LC‑MS, LC‑MS/MS) for identity, purity/impurity profiling, quantitation, and stability-indicating assessments
• Authoring methods, protocols and reports
• Ensuring data integrity and compliance within GxP environments
• Providing technical leadership for routine testing and investigations
• Mentoring of junior staff
• Applying GMP in all areas of responsibility, as appropriate
• Performing a large variety of analytical tasks for the validation of analytical methods used in the testing of drug products and raw materials by means of various procedures including HPLC, GC, UV/Vis, and dissolution
• Reading, understanding, and interpreting diverse analytical procedures
• Conducting analytical investigations
• Troubleshooting instrumentation and communicating with vendors when required
• Training and mentoring junior staff in laboratory procedures
• Managing and discussing projects with clients

Benefits

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

What This Job Offers

• Job Type: Full-time
• Career Level: Senior