Senior Medical Science Liaison (Texas/U.S. Oncology)

Tango Therapeutics • Boston, MA

6h • Remote

About The Position

The Senior MSL is a U.S. field-based role within Medical Affairs, reporting to the Executive Director, Medical Affairs. This role will be a core member of Tango’s growing field medical team during a critical phase of development. The Senior MSL will be responsible for high‑quality scientific exchange, trial execution support, medical education, and insight generation across priority solid tumor indications, with an initial focus on pancreatic cancer (PDAC), non-small cell lung cancer (NSCLC), and our evolving pipeline programs. This role is ideal for an individual who wants to operate at the intersection of clinical development, external scientific engagement, and launch readiness in a late-emerging biotech environment, where individual impact is high and scientific accountability matters.

Requirements

• 8 years of relevant experience with a bachelor’s degree, 6 years with a master’s degree, or 3 years with an advanced scientific or medical degree (e.g., PharmD, PhD, MD)
• Candidates with advanced clinical degrees (e.g., NP, PA) and significant oncology Medical Science Liaison experience will also be considered.
• Strong scientific acumen with the ability to engage deeply on complex biology and emerging clinical data
• Demonstrated strength in insight generation, synthesis, and communication
• Comfortable operating in a fast-moving, high-accountability biotech environment
• Excellent collaboration skills across matrixed teams
• Strong understanding of U.S. clinical research and healthcare environments
• Working knowledge of FDA, OIG, ICH, GCP, PhRMA Code, and applicable compliance standards
• Commitment to compliant, ethical scientific exchange
• Proficiency in standard business and field tools (CRM, MS Office, virtual engagement platforms)

Nice To Haves

• Experience in PDAC, GI malignancies, or NSCLC strongly preferred
• Prior experience supporting clinical-stage or pre-launch oncology assets highly valued

Responsibilities

• Build and sustain deep, credible relationships with priority investigators, KOLs, and emerging scientific leaders in PDAC and NSCLC
• Conduct high-quality, fair-balanced scientific exchange in response to unsolicited requests, grounded in a strong understanding of Tango’s biology, clinical data, and development strategy
• Serve as a trusted scientific partner on disease biology, treatment paradigms, and evolving standards of care, particularly in high-unmet-need settings such as PDAC
• Support Tango-sponsored clinical trials, with emphasis on: Site identification and activation, Enrollment support and investigator engagement, Ongoing scientific dialogue to enhance trial conduct
• Act as a Medical Affairs bridge between investigators and internal Clinical Development and Clinical Operations teams
• Contribute field-based perspective to protocol feasibility, study design considerations, and operational execution
• Capture and synthesize high-quality, hypothesis-driven insights from the field related to: Trial design and execution, Competitive landscape, Future evidence needs
• Translate insights into actionable feedback that informs Medical Strategy, Clinical Development, and future regulatory and commercialization readiness
• Contribute to refinement of Tango’s core scientific narrative as programs mature and data evolve
• Support planning and execution of advisory boards, investigator meetings, and other scientific forums
• Represent Tango at major medical and scientific congresses relevant to PDAC, NSCLC, and precision oncology
• Maintain up-to-date knowledge of relevant literature, competitive activity, and guideline evolution
• Collaborate closely with Medical Affairs leadership, Medical Content, Clinical Development, Regulatory, and other cross-functional partners
• Serve as a scientific resource to internal stakeholders
• Uphold the highest standards of compliance, scientific integrity, and ethical engagement

Benefits

• Medical Affairs team built for a transition from mid-stage to late-stage development
• Contribute directly to trial success, data readiness, and future regulatory and commercialization pathways
• Expand and establish Tango as a credible clinical scientific leader in precision oncology
• Work in a lean, collaborative environment where your scientific judgment and execution matter
• Equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior