Senior Manager, US Medical Affairs

Dyne Therapeutics • Waltham, MA

11h • $165,000 - $190,000 • Onsite

About The Position

The Senior Manager, US Medical Affairs supports the execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program. This role contributes to critical launch readiness activities and supports the planning and delivery of US Medical initiatives, including KOL engagement, congress execution, medical education efforts, and cross-functional coordination. The Senior Manager operates as both a scientific and operational contributor, helping prepare the US Medical organization for anticipated DMD program needs. This role partners closely with Medical Science Liaisons (MSLs), Global Medical Affairs, and cross-functional stakeholders to ensure medical activities are high-quality, compliant, and impactful. This role is based in Waltham, MA.

Requirements

• Advanced scientific or clinical degree required (PhD, PharmD, MD, or equivalent)
• 7+ years of relevant Medical Affairs experience in pharmaceutical or biotechnology industry
• Experience supporting US-based medical tactics, congress activities, or field medical programs
• Strong scientific acumen with ability to translate clinical data for diverse audiences
• Excellent written and verbal communication skills
• Ability to operate effectively in a fast-paced, evolving environment with competing priorities
• Demonstrated ability to build collaborative relationships with internal and external
• Positive team orientation with strong alignment to Dyne’s Core Values
• Passion for improving the lives of patients with neuromuscular diseases

Nice To Haves

• Rare disease experience preferred
• Neuromuscular disease experience a plus

Responsibilities

• Supports execution of US Medical Affairs tactical plans for the DMD program
• Assists in implementing scientific platform materials, congress planning, and medical education initiatives
• Contributes to cross-functional launch readiness activities to ensure alignment with program milestones
• Supports development and deployment of DMD-focused scientific materials, disease state education resources, and field medical tools
• Partners with the US MSL team to support KOL identification, engagement planning, insight gathering, and field metric tracking
• Translates field insights into actionable recommendations for Medical Affairs and cross-functional teams
• Tracks and monitors field activity and engagement effectiveness
• Contributes to development of scientific materials, field tools, and educational content
• Provides Medical review for promotional materials through the Promotional Review Committee (PRC)
• Maintains deep and current scientific knowledge in DMD and Dyne’s therapeutic platform
• Supports planning and execution of medical congresses, including onsite activities aligned to DMD milestones
• Coordinates logistics and execution of US advisory boards and expert engagements
• Partners with Patient Advocacy, Market Access, and Commercial teams to support aligned medical activities
• Ensures all activities comply with US regulatory, legal, and compliance standards
• Models Dyne’s core values through collaboration, accountability, and scientific integrity

Benefits

• The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree