Senior Manager, IT Operations

RepliGen CorporationWaltham, MA
$143,100 - $200,000

About The Position

Repligen is seeking a Senior Manager, IT Operations to lead global Tier 2 and platform operations across a multi-site environment supporting manufacturing, laboratory (OT), and corporate functions. This is a high-impact leadership role at the center of our IT organization—owning service stability, operational performance, and user experience across a rapidly growing global footprint. We are looking for a hands-on, player-coach leader who can drive execution, elevate team capability, and bring structure and discipline to a distributed operations environment.

Requirements

  • 12+ years of IT experience, including 5+ years leading infrastructure or operations teams
  • Proven ability to build, develop, and elevate global technical teams
  • Strong hands-on experience with: Microsoft Entra ID and Active Directory
  • Azure and hybrid infrastructure (AWS experience a plus)
  • Endpoint management (Intune; SCCM a plus)
  • Enterprise patching, compliance, and device lifecycle management
  • Microsoft 365 ecosystem
  • Experience with ITSM tools and frameworks (ServiceNow required; ITIL strongly preferred)
  • Demonstrated ability to improve operational performance through KPIs, SLAs, and process maturity
  • Experience managing vendors and third-party service providers
  • Understanding of structure operations in regulated or manufacturing environments.
  • Experience with disaster recovery, business continuity, and capacity planning
  • Strong leadership, communication, and stakeholder management skills
  • Operational mindset with a focus on reliability, scalability, and continuous improvement
  • Experience building and scaling high-performing global teams, driving capability growth while fostering a collaborative, service-oriented culture

Nice To Haves

  • AWS experience
  • SCCM experience
  • ITIL strongly preferred
  • Microsoft certifications

Responsibilities

  • Lead and develop a global IT operations team, driving accountability, performance, and service excellence
  • Own service delivery performance, including MTTR, SLAs, backlog, and end-user satisfaction
  • Establish and enforce a clear Tier 1 / Tier 2 / Tier 3 operating model
  • Lead major incident management and drive timely resolution and root cause analysis
  • Mature and enforce ITIL processes (incident, problem, and change management) using ServiceNow
  • Define and track operational KPIs and reporting to provide visibility into service performance
  • Oversee hybrid structure operations across Azure and on-prem environments
  • Manage identity services across Active Directory and Microsoft Entra ID
  • Lead endpoint and device management strategy, including Intune, SCCM, and Autopilot
  • Ensure enterprise patching, endpoint compliance, and secure configuration management
  • Manage vendors, managed service providers, and third-party partners, including SLAs and performance
  • Contribute to IT operations budgeting, cost control, and resource planning
  • Own disaster recovery, business continuity readiness, and capacity planning across global environments
  • Partner with manufacturing, laboratory (OT), and cross-functional IT teams to drive reliability, standardization, and continuous improvement

Benefits

  • paid time off
  • health/dental/vision
  • retirement benefits
  • flexible spending accounts
  • variable cash programs (bonus or commission)
  • equity as part of the compensation package
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