Senior Manager, Forecasting & Analytics

Sarepta TherapeuticsCambridge, MA
$136,000 - $170,000Hybrid

About The Position

The Senior Manager, Forecasting and Analytics reports to the Director, Forecasting and Launch Readiness and is responsible for building robust commercial forecasts, generating decision-ready analyses, and developing perspectives that support the commercial success of Sarepta’s in-line and pipeline portfolio. This role partners closely with cross-functional stakeholders, including Competitive Intelligence, Market Research, Sales, Finance, Business Performance, Market Access, Patient Services, and International Business, to develop pressure-tested forecasts, commercial perspectives, and business targets.

Requirements

  • Bachelor’s degree with 7-9 years of experience in a scientific, quantitative, or statistics-related field required
  • 5+ years of forecasting and analytics experience in biopharma
  • Excellent communication skills, with the ability to distill insights and forecast perspectives for Commercial Leadership, Executive Committee, and Board discussions.
  • Experience using AI tools and agents to automate recurring analyses and support deeper insight generation.
  • Strong analytical mindset with solid quantitative skills.
  • Advanced proficiency in Excel, Tableau, or similar data visualization and analysis tools.
  • Exceptional attention to detail.
  • Strong logical and critical thinking skills, including the ability to perform quick, reliable back-of-the-envelope analyses for leadership discussions.
  • Strong project management skills, with the ability to manage multiple priorities simultaneously.

Nice To Haves

  • master’s degree with 5-7 years of experience strongly preferred
  • rare disease experience preferred
  • consulting experience a plus
  • Preferred experience with advanced analysis using SQL, Python, or similar languages.

Responsibilities

  • Build, own, and maintain lifecycle-appropriate forecasting models for Sarepta’s U.S. and global in-line and pipeline portfolio.
  • Develop forecast scenarios, sensitivity analyses, business opportunity estimates, and near- and long-term therapy adoption projections.
  • Translate strategic, operational, and financial drivers into robust forecast assumptions and models.
  • Evolve forecasting capabilities through model refreshes, scenario analyses, and variance reporting in partnership with key stakeholders.
  • Support planning processes, including S&OP, LRP, and LEs, ensuring risks and uncertainties are reflected in commercial decisions.
  • Support quarterly HCP targeting activity for four in-market products to support demand generation and sales execution.
  • Lead development and management of forecast models for pipeline therapies, including SiRNA programs.
  • Drive ad hoc analyses to refine assumptions and support board and leadership discussions.
  • Produce periodic demand forecasts in collaboration with Commercial, Finance, and Tech Ops.
  • Monitor market dynamics and update forecasts to reflect relevant industry and therapeutic-area developments.
  • Build strong cross-functional relationships with key collaborators.
  • Perform other related duties as needed.

Benefits

  • Physical and Emotional Wellness
  • Financial Wellness
  • Support for Caregivers
  • competitive compensation and benefit package
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