Senior Manager, Clinical Supply Integration

Olema Oncology•San Francisco, CA

3d•$150,000 - $160,000•Hybrid

About The Position

As the Senior Manager, Clinical Supply Integration reporting to the Vice President, Clinical Supply Chain, you will oversee the end-to-end flow of investigational medicinal products (IMPs), from manufacturing through packaging and labeling, QP release, logistics, clinical depots, and trial sites. Serving as the central point of coordination across external providers and internal study teams, you will ensure plans are executable, lead times and dependencies are visible, risks are identified and addressed early, and medicines reach patients safely and on time. In addition you will partner closely with Clinical Operations, CMC, Quality, Regulatory, Finance, and external vendors to support global clinical programs as Olema continues to advance its pipeline. This role is based out of our San Francisco or Boston office and will require 10-15% domestic or international travel.

Requirements

Bachelor's degree is required; master's degree is preferred
Strong understanding of end-to-end global clinical supply operations
Working knowledge of GMP, GDP, Quality, Clinical Operations, and regulatory requirements
Familiarity with clinical supply, QMS, planning, project management, and data/reporting systems
Minimum of 8+ years of progressive clinical supply experience with a Bachelor’s degree, or 6+ years with a Master’s degree, within the biotechnology or pharmaceutical industry; experience supporting complex global and/or late-stage studies preferred
Demonstrated experience coordinating end-to-end clinical supply activities across manufacturing, packaging and labeling, release
Strong project management and data reconciliation skills, with demonstrated ability to investigate discrepancies and drive issues through resolution
Strong vendor management and governance experience, including performance monitoring, issue escalation, and resolution
Clear, concise communicator who can influence without direct authority
Strong analytical judgment, problem-solving, and risk-management skills, with the ability to identify issues early and escalate appropriately
Highly organized and capable of managing multiple complex timelines, priorities, and dependencies simultaneously
Strong sense of ownership and accountability, with consistent follow-through from planning through execution
Collaborative and effective at building productive relationships across internal teams and external partners
Hands-on and operationally minded, proactive, pragmatic, and committed to continuous improvement and operational excellence
Strong commitment to patients, teamwork, quality, and results

Nice To Haves

Previous exposure to inventory, demand, logistics, and distribution preferred
Oncology clinical trial experience preferred

Responsibilities

Lead coordination of clinical supply activities across global CDMOs in the US, EU, UK, APAC, and LATAM, managing multiple timelines, dependencies and linked deliverables
Oversee project logistics for packaging and labeling, procurement, and manufacturing runs, aligning activities across Clinical Supply, Clinical Operations, Quality, Regulatory, and CMC
Partner with internal supply chain team and external vendors to ensure timely execution and appropriate identification and escalation of issues
Maintain supply timelines for all clinical programs, including supply protocols, procedures, systems and documentation management
Partner with the Vice President, Supply Chain and Finance to support and manage departmental budgets, monitor project progress, and ensure packaging, labeling, and global distribution are properly planned and executed
Identify operational gaps and drive cross-functional continuous improvement initiatives, implementing SOPs, lessons learned, and best practices to strengthen and scale clinical supply operations as the portfolio grows