Senior Manager, Clinical Scientist, Genetics Medicine

Regeneron Pharmaceuticals

8d • $150,500 - $245,500 • Hybrid

About The Position

Regeneron Genetics Medicine is seeking a Senior Manager to join its Clinical Sciences team and support early clinical development in a fast-paced, collaborative environment. The role contributes to clinical strategy and study execution from discovery through Proof of Concept, helping translate genetic insights into potential treatments. The Senior Manager collaborates with their supervisor, Clinical Trial Managers, and cross-functional study teams.

The position represents the clinical genetics medicine function on study teams and provides medical and scientific expertise to support compliant, high-quality trial execution. It contributes to clinical study concepts, protocols, amendments, and clinical sections of regulatory and clinical documents; reviews key study materials; supports medical monitoring and safety and efficacy data analysis; and helps identify and mitigate program, trial, and data risks. The role also supports study-team and CRO training and organizes committees, boards, and consultations with global subject matter experts.

The role is based in Tarrytown, New York; Warren, New Jersey; or Cambridge, Massachusetts. Work is primarily on-site, with hybrid flexibility. The annual salary range is $150,500 to $245,500.

Requirements

• Bachelor’s degree.
• At least 8 years of clinical research or development experience.
• Training as a scientist in the pharmaceutical or biotechnology sector, or in an academic or clinical setting.
• Effective verbal and written communication and presentation skills.
• Ability to work productively in a fast-paced, collaborative environment.
• Demonstrated or potential critical-thinking skills and sound decision-making.

Nice To Haves

• PhD, PharmD, or master’s degree in a biomedical subject.
• Experience in early-phase development, including First-In-Human and Proof of Concept studies.

Responsibilities

• Represent the clinical genetics medicine function on study teams, contributing medical and scientific expertise to compliant, high-quality trial execution.
• Contribute to clinical study concepts, protocols, and amendments, supported by literature research on indication selection, rationale, and endpoints.
• Draft clinical sections of regulatory and clinical documents, including briefing books, IND/IMPD submissions, investigator’s brochures, consent forms, and study reports.
• Review key study documents, including medical monitoring plans, statistical analysis plans, and data management materials.
• Partner with Clinical Trial Managers to provide day-to-day clinical input and train study team and CRO personnel on clinical aspects of the trial.
• Support medical monitoring, investigator queries, safety narratives, and trend analysis of safety and efficacy data.
• Organize steering committees, advisory boards, data safety monitoring boards, and consultations with global subject matter experts.
• Identify program, trial, and data risks and implement mitigation strategies while ensuring compliance with FDA, EMEA, ICH, and GCP guidelines.

Benefits

• Annual bonuses or other incentive plans may be offered, depending on country and role.
• Equity awards may be offered, depending on country and role.
• Pension or retirement benefits may be offered, depending on country and role.
• 401(k) company match may be offered, depending on country and role.
• Health and wellness programs may be offered, depending on country and role.
• Fitness centers may be available, depending on country and role.
• Insurance benefits may include medical, dental, vision, life, and disability coverage, depending on country and role.
• Paid time off may be offered, depending on country and role.
• Family support benefits may be offered, depending on country and role.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior