Senior Manager, Clinical Pharmacology
About The Position
The Senior Manager, Clinical Pharmacology role sits within Quantitative Clinical Pharmacology and Biosimilar Sciences (QPB), part of Global Early Clinical Development (GEC). This position plays an important role in supporting early clinical development programs by contributing to integrated clinical pharmacology strategies, study design, and data interpretation. Working under the guidance of experienced leaders, this role operates at the program level, collaborating closely with clinical teams, Pharmacometrics (PMX), and Translational & Precision Medicine (TPM). The position offers a strong opportunity to build depth in clinical pharmacology while progressively developing scientific judgment, independence, and leadership capability. This role is also expected to help bring modern, data‑driven approaches into day‑to‑day clinical pharmacology work, including the thoughtful use of AI‑enabled analytics and advanced data science tools to enhance efficiency, insight generation, and innovation across QPB and GEC. This role can be based out of West Chester, PA or Parsippany, NJ and will follow a hybrid schedule.
Requirements
- Master’s, PharmD, or PhD in clinical pharmacology, pharmaceutical sciences, medicine, or a related field required. PhD preferred.
- A minimum of 3 years of experience in clinical pharmacology or closely related areas (e.g., clinical pharmacokinetics, DMPK, regulatory science), preferably within the pharmaceutical or biotechnology industry.
- Foundational understanding of quantitative approaches such as PK, PK/PD, and exposure–response analyses.
- Strong analytical thinking and attention to scientific detail.
- Ability to work effectively in a matrixed, cross‑functional, and global environment.
- Clear written and verbal communication skills in English.
- Curiosity, adaptability, and motivation to learn and grow within a fast‑paced development environment.
Nice To Haves
- Exposure to early clinical development and clinical pharmacology study design and interpretation.
- Interest in, or early experience with, data science, automation, or AI‑enabled analytical tools applied to clinical or pharmacological data.
- Experience in immunology, respiratory, and/or CNS therapeutic areas.
- Experience contributing to regulatory interactions or submissions.
- Interest in innovation and continuous improvement in drug development processes.
- Experience presenting scientific results to diverse internal audiences.
Responsibilities
- Support clinical pharmacology activities for assigned programs across the entire development lifespan, contributing to integrated clinical and regulatory strategies aligned with program objectives.
- Contribute to the planning, execution, analysis, and interpretation of clinical pharmacology studies, including first‑in‑human and other Phase 1 trials.
- Contribute to dose selection, dose escalation, and exposure–response understanding by integrating clinical PK/PD data with quantitative insights developed in collaboration with Pharmacometrics.
- Partner with Translational & Precision Medicine colleagues to align biomarkers, mechanistic insights, and translational strategies with early clinical development plans.
- Support preparation of clinical pharmacology content for key documents, including clinical development plans, protocols, investigator brochures, clinical study reports, and regulatory submissions.
- Leverage emerging analytical approaches, including AI‑enabled and advanced data science tools, to improve data interpretation, efficiency, and innovation in clinical pharmacology deliverables.
- Contribute to a collaborative team culture within QPB and GEC, sharing knowledge and continuously developing technical and scientific capabilities.
Benefits
- Comprehensive Health Insurance: Medical, Dental, Vision, and Prescription coverage starting on the first day of employment, providing the employee enrolls.
- Retirement Savings: 401(k) with employer match, up to 6% and an annual 3.75% Defined Contribution to the 401k plan.
- Time Off: Paid Time Off including vacation, sick/safe time, caretaker time and holidays.
- Life and Disability Protection: Company paid Life and Disability insurance.
- Employee Assistance Program
- Employee Stock Purchase Plan
- Tuition Assistance
- Flexible Spending Accounts
- Health Savings Account
- Life Style Spending Account
- Volunteer Time Off
- Paid Parental Leave, if eligible
- Family Building Benefits
- Virtual Physical Therapy
- Accident, Critical Illness and Hospital Indemnity Insurances
- Identity Theft Protection
- Legal Plan
- Voluntary Life Insurance and Long Term Disability
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What This Job Offers
Job Type
Full-time
Career Level
Senior
