Senior HVAC Maintenance Technician

AstraZeneca•Los Angeles, CA

23h•Onsite

About The Position

This role is responsible for leading preventive, predictive, and corrective maintenance across a variety of HVAC systems, ensuring compliance with GMP standards and optimizing building management systems. The technician will also be involved in calibration, validation support, investigations, and driving improvements in energy efficiency and system performance. The position requires a strong understanding of cleanroom environments and safety protocols, with opportunities for mentorship and cross-functional collaboration.

Requirements

Technical diploma/apprenticeship in HVAC/Mechanical/Building Services
6–10+ years in HVAC maintenance
3–5 years in pharma/biotech or regulated GMP environments
Cleanroom HVAC experience is essential
Strong controls/BMS proficiency (PID, trends, data integrity)
Knowledge of ISO cleanroom classifications, airflow visualization/smoke studies, pressurization cascades, aseptic requirements
Experience with sensor calibration, IQ/OQ/PQ, GDP, CAPA, Change Control
Advanced troubleshooting skills
Basics of vibration analysis and thermography
Proficiency with instrumentation (anemometers, micromanometers, particle counters, data loggers)
Clear communication, teamwork, stakeholder management, decisive under time pressure, meticulous documentation
Ability to lift 50 lbs, work on ladders/at heights/in mechanical spaces, wear PPE for labs/cleanrooms
Willingness to participate in after-hours/on-call rotation

Nice To Haves

Bachelor’s in Mechanical/Building is a plus
Safety training preferred
Manufacturer training on chillers/controls
GxP/cleanroom courses are a plus

Responsibilities

Lead preventive/predictive/corrective maintenance across AHUs, chillers, boilers, heat exchangers, VAVs, exhaust, dehumidifiers, and split systems, owning temperature, humidity, airflow, and pressurization in GMP spaces.
Ensure cleanroom compliance with ISO 14644: HEPA integrity, airflow patterns, recovery times, and differential pressures; support aseptic areas and gowning zones.
Optimize and troubleshoot BMS/EMS/SCADA (Siemens, Allen-Bradley, Johnson Controls): tune PID loops, rationalize alarms, adjust sequences of operation, and document via change control.
Coordinate calibration (temperature, RH, pressure, flow) and support IQ/OQ/PQ with solid validation documentation.
Drive investigations and CAPA using RCA methods (5-Why, Fishbone) and maintain impeccable cGMP/GDP records and SOPs.
Champion audit readiness (FDA/EU GMP) and keep systems in a validated state.
Improve energy and performance: VFDs, heat recovery, demand-based ventilation, and smart control strategies.
Plan and execute outages/turnarounds/capital projects with contractors, materials, and risk assessments.
Lead safety culture (LOTO, confined space, hot work, arc-flash; EPA 608 refrigerants) and mentor junior techs.
Manage spares and CMMS workflows; partner closely with Quality, Manufacturing, Engineering, Validation, and Operations.