Senior Director, Global Medical Director, GI Tumors

Jazz Pharmaceuticals • Philadelphia, PA

6d • Remote

About The Position

The Senior Global Medical Director, Gastrointestinal Cancers is a strategic role with execution responsibilities on Jazz Pharmaceuticals’ Global Commercialization Organization Medical Affairs Oncology team. Reporting to the VP, GCO Medical Affairs, Oncology, this position represents the needs and priorities of the US, as lead region, and EUR/INT regions across global cross-functional teams and decision-making forums. The role partners closely with regional Medical Affairs colleagues to ensure customer, patient, healthcare provider, and healthcare system needs are understood and considered in clinical development, evidence generation, and lifecycle planning.

The role leads the GI Cancer Global Medical functional matrix team and serves as an interface between regional Medical Affairs teams and global R&D, Global Product Development, and Commercialization functions. It contributes Medical Affairs expertise to early development, including Target Product Profile development, clinical trial design, and lifecycle planning; leads evidence-generation and publication strategies; and supports scientific communications, congress planning, advisory boards, and external engagement. The position also provides Medical Affairs input into the Payor Value and Evidence Plan and acts as a subject matter expert for internal stakeholders.

The role requires at least 10 years of Medical Affairs, Clinical Development, or related pharmaceutical or biotechnology industry experience and an advanced scientific or healthcare degree. GI cancer and/or HER2-targeted therapy experience is strongly preferred. For US-based candidates, the stated base pay range is $268,000–$402,000, with potential discretionary incentive compensation and equity grants. Benefits include medical, dental, and vision insurance, a 401(k) retirement savings plan, and flexible paid vacation.

Requirements

• At least 10 years of Medical Affairs, Clinical Development, or related pharmaceutical or biotechnology industry experience.
• Demonstrated experience developing and executing evidence-generation strategies, publication plans, and external scientific engagement activities.
• Strong understanding of clinical research, evidence generation, and oncology drug development.
• Proven ability to influence without authority and work effectively in complex matrix organizations.
• Strategic thinking and strong operational execution skills.
• Excellent written, verbal, presentation, and stakeholder-management skills.
• Ability to build productive partnerships across regions and functions and represent diverse stakeholder perspectives effectively.
• Ability to manage multiple priorities and deliver high-quality outcomes in a fast-paced environment.
• Self-awareness and emotional intelligence, including ability to navigate complex matrix environments.
• Advanced scientific or healthcare degree required, such as PharmD, PhD, MD, MBBS, Nurse Practitioner, PA, or equivalent.

Nice To Haves

• Oncology experience is preferred.
• Experience in GI cancers and/or HER2-targeted therapies is strongly preferred.
• Experience in lifecycle management of oncology indications is strongly desired.
• Experience in the delivery of oncology care is preferred.
• Evidence of success in matrix organizations, including independent critical thinking, initiative, and execution under time pressure with competing priorities.

Responsibilities

• Lead the GI Cancer Global Medical functional matrix team.
• Partner with US and EUR/INT Medical Affairs teams to understand regional customer, patient, healthcare provider, and healthcare system needs and priorities.
• Represent and advocate for medical perspectives in global cross-functional teams and governance forums, including CDT, LDT, PGC, and DPRC.
• Contribute Medical Affairs expertise to early development activities, including Target Product Profile development, clinical trial design, and lifecycle planning.
• Ensure regional needs and insights are considered in clinical development discussions, evidence-generation activities, and lifecycle planning.
• Maintain and apply knowledge of the competitive landscape to inform evidence-generation strategy and internal development decisions.
• Lead development, maintenance, and execution of the Integrated Evidence Generation Plan for the Solid Tumor Oncology Product in BTC and Gastroesophageal Cancer and other GI malignancies as assigned.
• Partner across Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, HEOR, RWE, Commercial, and other teams to support evidence generation and scientific exchange.
• Lead and support evidence-generation activities, including investigator-sponsored studies, real-world evidence initiatives, health outcomes research, and Phase IV interventional studies where appropriate.
• Lead development of the breast cancer medical narrative by identifying and advancing analytic needs and informing interpretation of pivotal trial data.
• Provide Medical Affairs leadership and input into the Payor Value and Evidence Plan.
• Lead development and execution of publication strategy and evidence dissemination plan aligned with regional evidence needs and scientific priorities.
• Support scientific communications, congress planning, advisory boards, and external engagement activities as required.
• Act as a subject matter expert for internal cross-functional stakeholders.

Benefits

• Medical insurance
• Dental insurance
• Vision insurance
• 401(k) retirement savings plan
• Flexible paid vacation
• Potential discretionary annual cash bonus or incentive compensation, depending on the role
• Potential discretionary equity grants

What This Job Offers

• Job Type: Full-time
• Career Level: Senior