Senior Engineer I, Manufacturing Sciences  - Purification

Biogen • Research Triangle Park, NC

3d • Onsite

About The Position

The Senior Engineer I, Manufacturing Sciences serves as a key scientific resource supporting biologics purification for drug substance manufacturing at Biogen’s RTP facility. This role enables successful production of biopharmaceuticals by designing and executing laboratory studies, leading downstream process transfers into GMP manufacturing, and providing scientific support to ongoing commercial operations.

Requirements

• Bachelor’s degree in relevant scientific or technical fields from an accredited college or university
• At minimum 4 years of directly relevant industry or industry-adjacent experience
• Familiarity with biopharmaceutical manufacturing and/or downstream processing
• Previous experience with some or all of the following: design experiments, analyze data, and/or execute laboratory studies
• Willingness and ability to work on-site more frequently during training periods, critical projects, audits, etc.

Nice To Haves

• Bachelor’s degree in engineering or life science
• Demonstrated experience leading complex scientific projects related to purification
• Previous experience performing root cause analysis and risk-based technical assessments
• Experience supporting deviations, change controls, CAPAs, and regulatory documentation
• Prior experience acting as a technical lead or SME within a manufacturing support organization

Responsibilities

• Provide deep technical expertise in biologics purification: chromatographic separations, viral filtration, and UF/DF to support technology transfer and process improvement initiatives
• Design, plan, execute, and document laboratory studies to improve process robustness, enhance process understanding, and troubleshoot manufacturing issues
• Lead cross-functional project teams and collaborate with Technical Development, Engineering, and GMP Manufacturing
• Support downstream GMP operations, including process transfer activities and ongoing manufacturing campaigns
• Serve as technical SME for investigations, performing root cause analysis and implementing effective corrective and preventive actions (CAPAs)
• Represent manufacturing in change controls, continuous improvement initiatives, capital projects, and new component introductions
• Support process validation activities, including batch execution and authoring technical summary reports
• Analyze manufacturing data and experimental results, clearly communicating insights and recommendations to stakeholders

Benefits

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level