Senior Director, US Rare Disease Value and Access

Sanofi•Cambridge, MA

4d•Onsite

About The Position

Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you'll own payer-focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. You'll be joining Sanofi's US Rare Disease business at a pivotal moment—managing market access for a portfolio with clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay. The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy — working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch. Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI-augmented evidence and value work.

Requirements

Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred
10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms
7+ years of leadership experience managing teams and cross-functional initiatives
Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management
Proven track record in GTN management and financial modeling
Strong financial acumen including P&L impact and pricing strategy
Experience with value proposition development and payer evidence generation
Experience in rare disease or specialty therapeutics preferred
Excellent communication, negotiation, and executive influence skills
Ability to navigate complex, highly regulated environments while managing multiple priorities

Nice To Haves

AI-augmented judgment: Uses data and AI to decide faster and better — while owning the judgment calls AI cannot make.
Orchestrates across boundaries: Delivers through influence, shared goals, and trust as functional silos dissolve — not through positional control.
Drives change and adoption: Pulls the team through AI and digital change, creates psychological safety to experiment, and names resistance rather than tolerating it.
Obsesses over the patient outcome: Anchors decisions to the patient's find-to-adherence journey, not functional activity metrics; treats advocacy and equity as strategic.
Models learning agility: Reskills continuously, experiments, and fails fast in the open so the team does the same.
Builds talent density: Runs lean with an elite bar: a few exceptional people, amplified by AI, outproduce larger teams. Makes the hard talent calls, raises the standard, and develops those they keep.

Responsibilities

Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio
Develop evidence-based market access strategies that maximize formulary adoption and patient access
Create compelling value propositions for payers, providers, and key stakeholders
Oversee and optimize GTN across the therapeutic area—pricing, rebates, and discounts by channel
Monitor GTN performance and deliver recommendations to senior leadership to protect profitability
Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales
Lead GTN pull-through across all channels and geographies based on formulary position
Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access
Develop primary payer research and advisory board programs to close market access knowledge gaps
Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions
Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions
Define KPIs and track progress against access and financial targets
Balance brand objectives and patient access priorities when they are in conflict
Build, develop, and lead a high-performing team of 2 direct reports