Senior Director, Program Team Lead

Editas Medicine•Cambridge, MA

6h•$265,000 - $290,000

About The Position

At Editas Medicine, our mission and commitment is to harness the power and potential of CRISPR gene editing to develop a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable genomic medicines for many diseases. The primary focus of this role in the next 12 months is to advance our lead in vivo development candidate, EDIT-401, by leading program strategy and driving disciplined, cross-functional execution, proactively managing risk, and ensuring alignment between scientific ambition and operational reality. EDIT-401 is a potential best-in-class, one-time therapy designed to significantly reduce LDL cholesterol levels. This is a critical and highly visible role, making a substantial contribution to the company, with the opportunity to expand as pipeline therapies advance in development.

Requirements

A minimum of a bachelor’s degree in life sciences or related subjects
10+ years of experience in biotech/pharma, with 8+ years in program management supporting early-stage clinical development.
Proven track record of leading cross-functional teams in a matrixed environment
Excellent relationship building skills and ability to earn trust and align diverse perspectives towards a shared goal
Strong understanding of preclinical development, IND-enabling studies, and early clinical trial operations.
Expert planning and tracking skills with mastery of project management tools and methodologies(e.g., Smartsheet, Microsoft Project, Office Timeline)
Comfort operating with urgency, limited infrastructure, and ambitious priorities

Nice To Haves

advanced degrees (Ph.D or MBA) are desirable
Experience managing multiple programs at the same time is desirable
Solid understanding of science and experience with gene therapy programs is highly desirable
Experience across functional roles is desirable
Desirable leadership attributes include holding teams accountable with clarity and respect, and demonstrating impact with a focus on delivering outcomes.

Responsibilities

Lead the Program Team, responsible for creating and developing the program strategy, goals, milestones, and operational plan including realistic timelines, budget and resource planning, risk assessment and mitigation planning in collaboration with functional heads
Enable high‑quality, on time governance decisions and drive decision-making and issue resolution within the team, pulling on applicable subject matter expertise as needed
Ensure cross‑functional alignment and accountability for execution of the operational plan with a focus on high impact activities, establishing clear owners, dependencies, and timelines across Nonclinical, CMC, Quality, Regulatory, and Development
Responsible for dissemination of comprehensive, timely, and high-quality program information to Senior Management, including appropriate escalation of issues as may be required
Continuously pressure-test timelines and critical paths, proactively identifying opportunities to streamline execution without compromising quality or budget
Establish proactive risk identification and mitigation frameworks, surface issues, and drive for their resolution
Leads ad-hoc cross-functional task forces, as needed, aiming at issue resolution or organizational efficiency
Challenges assumptions, timelines, and expenses at program level, pressure tests plan, creates alternative scenarios to enable strategic and operational agility
Own the program-level budget, resource planning, and scenario assessments (evaluating cost, risk, and timelines) in collaboration with functional management
Build credibility and trust through recognition by functional leaders as a value‑adding, enterprise-minded, decision‑enabling partner