Senior Director, Pipeline Commercial Strategy

Iovance Biotherapeutics

2h•$270,000 - $290,000

About The Position

The Senior Director, Pipeline Commercial Strategy owns the commercial assessment of Iovance’s pipeline assets and indication expansions. The role quantifies market opportunities, develops commercially grounded target product profiles, evaluates competition, and represents reimbursement and market analyses from early development through launch. It shapes portfolio and indication strategy and drives priority workstreams from upstream pipeline development through launch readiness. The role defines actionable commercial strategies, workplans, timelines, and readiness deliverables based on expertise in oncology markets, treatment paradigms, and cell therapy commercialization. It represents Commercial in enterprise forums such as PDT and GDT and works across functions to align stakeholders and support investment, development, and launch decisions. The position operates in a professional or remote office environment and requires the use of standard office equipment and keyboards. The stated annual base salary range is $270,000–$290,000. Individual pay decisions may depend on work location, role complexity and responsibility, duties and requirements, and relevant education, experience, and skills.

Requirements

Bachelor’s degree required.
Typically 10+ years of experience in biopharmaceutical, biotech, oncology, cell therapy, specialty medicine, commercial strategy, launch planning, brand strategy, market access, consulting, or related fields.
Hands-on experience building market-sizing and addressable-market models, target product profiles, competitive assessments, and reimbursement or payer analyses for oncology or cell therapy assets.
Deep commercial domain expertise, including personally shaping commercial strategy and making market-facing decisions rather than solely managing timelines or coordinating workstreams.
Demonstrated ability to lead complex cross-functional initiatives, develop data-grounded strategic recommendations, and influence senior stakeholders through expertise and credibility.
Track record of leading product launches, new product planning, commercial assessments, forecasting, portfolio strategy, or launch readiness as a strategic driver rather than a project manager.
Strong executive presence, written communication, and analytical thinking, with the ability to influence without authority in a matrixed environment.

Nice To Haves

Advanced degree such as an MBA, MPH, PharmD, PhD, or relevant graduate degree.

Responsibilities

Own commercial assessments of pipeline assets and indication expansions, including market sizing, addressable market analysis, target product profiles, competitive analysis, and reimbursement market analysis from early development through launch.
Define and drive actionable commercial strategies, workplans, timelines, and readiness deliverables informed by oncology markets, treatment paradigms, and cell therapy commercialization.
Represent Commercial in enterprise forums such as PDT and GDT, serving as a strategic integrator who drives alignment through expertise.
Build market-sizing and addressable-market analyses by tumor type, line of therapy, and geography, using epidemiology, treatment-flow, and claims data.
Develop and maintain commercially grounded target product profiles for pipeline assets, defining efficacy, safety, dosing, and differentiation thresholds for target indications.
Own competitive analysis and scenario planning for pipeline indications, tracking competitor programs, data readouts, and approvals; model competitive entry, label variation, treatment landscape shifts, and outpatient usage opportunities; and define differentiation strategies.
Drive portfolio prioritization, forecasting, and commercial recommendations to inform Go/No-Go decisions for registrational trials.
Lead early commercial assessments for pipeline assets, indication expansions, in-licensing opportunities, acquisitions, and business development evaluations to inform investment decisions.
Provide commercial input on tumor target, indication, and launch-market selection, including signal-finding studies and investigator-sponsored trials that support future registrational trials.
Partner with Clinical Development and project teams to influence clinical milestones, trial design assumptions, accelerated or regular approval pathways, and regional commercialization considerations based on commercial viability and market dynamics.
Own launch trackers, readiness scorecards, risk registers, and milestone dashboards, using them to anticipate issues and drive proactive decision-making.
Adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
Perform miscellaneous duties as assigned.