Senior Director, Multiomics

Ginkgo Bioworks • Boston, MA

5d • Onsite

About The Position

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Senior Director, Multiomics – Ginkgo Datapoints Level (Sr. Director) will be set to match the successful candidate's experience. Location: Boston, MA (Seaport / HQ) Reporting to: General Manager, Ginkgo Datapoints Focus: Scientific Excellence, Commercial Strategy (P&L), Functional Genomics, Arrayed Perturbation Response Profiling & Multiomic Platform Expansion The Opportunity Ginkgo Datapoints defines the category of the Bio × AI data provider. We work with top pharma, biotech, tech, and techbio companies, and we've built our reputation on high-quality, large-scale, reproducible data generated by automation rather than by hand. We're a fee-for-service partner — our customers own their data, and our incentives are aligned with theirs. As our Senior Director of Multiomics, you will own the vision, execution, and commercial success of our Multiomics business, including the functional genomics engine behind our Perturbation Response Profiling and Specialized HTS offerings. This is a genuinely intrapreneurial role: you operate at the frontier of business and science, report to the GM of Datapoints, and lead a multidisciplinary team of scientists, automation engineers, and bioinformaticians with GS&A support. Your Mission Your primary goal is to scale our arrayed multiomic perturbation platform into the best in the industry, and to own the full P&L for the vertical. The near-term growth thesis is clear: Find new applications for DRUG-seq — safety first. Expand our high-throughput transcriptomic screening into new use cases, with safety and predictive toxicology chief among them. Turn perturbation data into AI fuel. Position our datasets as the training substrate for the next generation of AI/ML models, and shape data generation specifically to serve model training. Round out the readout menu. Extend beyond transcriptomics and imaging into proteomics, metabolomics, and additional NGS methods that complete a true multiomic offering. Build products the industry doesn't have yet. Add new offerings to the portfolio — arrayed whole-genome CRISPR knockouts paired with rich multiomic readouts among them — and the drug-discovery power that kind of capability unlocks. The role is anchored in discovery-stage functional genomics, with real room to extend our multiomic work into translational and clinical biomarkers — population-scale and direct-to-consumer rather than regulated diagnostics. If that's the work that excites you most, there's a home for it here.

Requirements

• 10+ years in high-growth biotech or large pharma with a proven track record in functional genomics and discovery research.
• You have been an active buyer of discovery / CRO / data-generation services (or led teams that were), and you're motivated to build, on the sell side, something you wished existed as a customer.
• PhD (or equivalent experience) in genomics, molecular biology, computational biology, systems biology, or a related field.
• You are a recognized expert in perturbation biology or modeling and the discovery cascade.
• Direct experience with arrayed chemical and/or genetic screening (CRISPR KO / CRISPRi), transcriptomic profiling, and high-content imaging.
• A strongly computational profile is very welcome — even ideal.
• What's essential is a firm, practical understanding of wetlab methods, so you can lead the experimental team credibly.
• You're excited to own the commercial side of a business — pricing, growth, and turning technical capability into customer value.
• You are an entrepreneur at heart.
• You thrive in fast-paced, high-stakes environments and are genuinely excited by the vision of a best-in-industry arrayed multiomics platform and the new products it can offer — arrayed whole-genome CRISPR knockouts among them.

Nice To Haves

• Translational and clinical biomarkers: experience — or a real passion for — biomarker work in population-scale or direct-to-consumer settings (rather than regulated diagnostics).
• Multiomic expansion expertise: proteomics, metabolomics, or additional NGS methods that would round out the offering.
• AI/ML or automation — ideally both: strength on either axis is a real asset.
• On the AI/ML side, experience using perturbation data to train models (MOA classification, perturbation embeddings, virtual-cell / gene-expression prediction).
• On the automation side, familiarity with how industrialized lab automation generates data at scale.
• Track record of contributing to commercial growth through scientific credibility, partnerships, or network relationships.
• Experience shaping or winning government / consortium grants.
• Established presence in the multiomics community (publications, speaking engagements, advisory roles).

Responsibilities

• Define the go-to-market strategy for Multiomics Datapoints.
• Identify market gaps, set pricing for our high-value / low-cost-per-datapoint model, and own revenue growth and operational efficiency across a customer base that spans large pharma, biotech, and government.
• Set the scientific direction across our arrayed perturbation platform and multiomic readouts — DRUG-seq (high-throughput transcriptomics), high-content imaging and Cell Painting (morphological profiling), and CRISPR-edit verification — across arrayed chemical, genetic (CRISPR KO / CRISPRi), and siRNA / ASO modalities.
• Drive the expansion agenda above: new DRUG-seq applications (especially safety), data purpose-built for AI/ML training, new readouts (proteomics, metabolomics, additional NGS), and new products such as arrayed whole-genome CRISPR knockouts.
• Lead and mentor a multidisciplinary team of roughly 10–15.
• Set direction, develop the team, and bridge the gap between industrialized wetlab automation and computational/AI interpretation.
• Serve as the face of Ginkgo's Multiomics business.
• Represent the company at major conferences (e.g., the Festival of Genomics), publish and present our science, and cultivate community around initiatives like the Virtual Cell Pharmacology Initiative (VCPI).
• Lend scientific credibility to sales and BD conversations, and open doors by connecting the commercial team with relevant contacts across your network.
• Partner with Government Affairs to shape and win large-scale programs (ARPA-H, BARDA, DARPA, NIH).
• Lead the continued scale-up of our automated arrayed perturbation-and-readout platform — transcriptomics, imaging, edit verification, and new omic layers — with integrated QC and AI analytics pipelines, to produce high-fidelity, AI-ready datasets faster and at greater scale than traditional labs.

Benefits

• Ginkgo has invested over $1 billion in automation infrastructure.
• We have some of the world's most advanced automated labs, and we are now making that power available to the world through Datapoints.
• This can't just be a job — you will be a driver of how the next generation of biology gets discovered.
• Ginkgo Datapoints is an equal opportunity employer.
• We source, evaluate, and hire candidates without regard to sex, gender, race, age, disability, or any other protected characteristic.
• We especially welcome applications from people who are underrepresented in scientific leadership.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree