Senior Director, HR Business Partner

Mirum Pharmaceuticals•Foster City, CA
•$270,000 - $290,000•Hybrid

About The Position

Mirum Pharmaceuticals is a biopharmaceutical company focused on transforming the treatment of rare diseases. The Senior Director, Human Resources reports to the VP, Global Human Resources, who is the HRBP for North America Commercial and Global Talent Development. The role partners with Technical Operations, Quality, and G&A leaders and employees, providing strategic HR guidance and solutions aligned with business objectives and company values. The Senior Director advises on HR initiatives, coaches leaders, fosters organizational effectiveness, and connects people strategies with business growth priorities. The role also partners with the VP, Global Human Resources to evolve and strengthen the HR Business Partner function, supporting consistency, effectiveness, and strategic impact across the organization.

Requirements

  • Bachelor’s degree in human resources or a related field.
  • 12 or more years of HR experience, or an equivalent combination of education and experience.
  • Ability to serve as a trusted advisor to senior leaders and translate business strategy into people, organization, and talent solutions within the biotechnology or pharmaceutical industry.
  • Experience supporting organizations through growth and transformation.
  • Strong business acumen and ability to understand operational, financial, and organizational drivers of performance and influence decisions across organizational levels.
  • Expertise in organizational effectiveness, organizational design, workforce planning, and change management, including diagnosing organizational challenges and implementing practical, scalable solutions.
  • Experience coaching and developing leaders and technical professionals.
  • Success leading talent reviews, succession planning, leadership development, and employee growth strategies.
  • Ability to use workforce data and people analytics to identify trends, anticipate risks, and support evidence-based decisions.
  • Strong consulting, facilitation, and relationship-building skills, including the ability to influence and navigate complex organizational dynamics without direct authority.
  • Skill in managing complex employee relations matters, conducting objective investigations, and providing actionable recommendations.
  • Excellent written, verbal, and interpersonal communication skills, with the ability to influence, educate, and build credibility across diverse audiences.
  • Strong knowledge of employment laws, HR practices, and compliance requirements in multi-state and global environments.
  • Ability to build, strengthen, and scale HR Business Partner capabilities and practices to deliver strategic value and organizational impact.

Responsibilities

  • Serve as a trusted advisor to senior leaders, translating business strategy into people, organization, and talent priorities that support growth and business performance.
  • Assess organizational effectiveness with leaders, design scalable organizational structures, and lead change initiatives that support business objectives.
  • Coach and develop leaders to strengthen leadership effectiveness and team performance, address complex employee and organizational issues, and build high-performing teams.
  • Lead workforce planning, talent management, succession planning, and leadership development strategies.
  • Partner with Talent Acquisition and business leaders to identify capability needs and develop strategies to attract, develop, engage, and retain talent.
  • Use workforce data, people analytics, and business insights to identify trends, assess risks, and influence talent and organizational decisions.
  • Facilitate talent reviews, performance management, and development planning processes to support accountability, growth, and high performance.
  • Partner with HR Centers of Excellence and global HRBPs to deliver integrated, consistent, and scalable people solutions.
  • Lead or contribute to enterprise-wide HR initiatives and programs that enhance employee engagement, organizational effectiveness, and the employee experience.
  • Manage complex employee relations matters, investigations, and organizational issues with sound judgment, objectivity, and compliance with company policies and employment laws.
  • Ensure compliance with applicable employment laws and regulations, and proactively identify and mitigate people-related risks.
  • Partner with the VP, Global Human Resources to evolve and strengthen the HR Business Partner function.
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