Senior Director, Head of Marketing

BridgeBio Pharma • San Francisco, CA

3d • $265,000 - $290,000 • Hybrid

About The Position

The Senior Director, Head of Marketing will serve as the commercial brand authority for Calci (encaleret) — BridgeBio's oral CaSR negative allosteric modulator in NDA review for Autosomal Dominant Hypocalcemia Type 1 (ADH1). This is a first-in-class asset targeting a chronically underserved rare endocrine population, and this role represents a defining commercial leadership opportunity. You will own the full marketing function for Calci: leading HCP marketing, patient marketing, and KOL engagement under a single integrated brand strategy. You will report directly to the SVP, Sales & Marketing — Endocrinology and will be expected to be on-site in both our San Francisco and Palo Alto home offices on a weekly basis. This is not a role for someone who needs a playbook. It's a role for someone who writes one.

Requirements

• 12+ years of commercial biotech or pharmaceutical experience, with at least 7 years in pharmaceutical/biotech marketing
• Prior people management experience required; experience building or scaling a marketing team in a launch setting strongly preferred
• Rare disease launch experience required — endocrinology or nephrology experience is a significant differentiator
• Demonstrated success owning brand strategy through launch, including brand planning, promotional development, and commercial execution
• Proven track record leading KOL engagement programs and commercial advisory board design
• Experience developing and managing both HCP and patient marketing strategies simultaneously
• Comfort operating in a pre-launch, high-ambiguity environment — able to set direction and drive execution before full commercial infrastructure is in place
• Strong working knowledge of FDA promotional guidelines, fair balance, and rare disease compliance requirements
• Exceptional oral, written, and executive presentation skills — including comfort with BOD-level deliverables
• Ability to travel (~25%) for key congresses, advisory boards, and field engagement
• Bachelor's degree required

Nice To Haves

• MBA or advanced science degree preferred

Responsibilities

• Own the Calci brand strategy end-to-end — positioning, messaging architecture, segmentation, and go-to-market sequencing — ensuring full alignment from pre-NDA approval through Year 1+ commercialization
• Lead all brand planning milestones, including annual brand plan, launch readiness assessments, and BOD-level commercial reporting
• Serve as the senior commercial voice on the Calci Product Team, embedding market realities into cross-functional planning across Medical Affairs, Regulatory, Market Access, and Patient Advocacy
• Build and maintain a dynamic competitive intelligence function, monitoring the ADH1 and broader hypoparathyroidism landscape and translating findings into strategic decisions
• Partner with Value & Access to shape the payer value proposition and ensure access strategies are integrated into brand planning from day one
• Directly lead and develop a team of 4, including: Director, HCP Marketing; Director, Patient Marketing; and two KOL Engagement Leads — setting individual performance goals, coaching toward professional growth, and building a cohesive, high-performing marketing organization
• Foster a culture of intellectual rigor, creative ambition, and patient-first accountability across the marketing team
• Act as the connector between team workstreams, ensuring HCP, patient, and KOL strategies are mutually reinforcing and aligned under one brand narrative
• Develop the next generation of commercial talent within the team through active mentorship, stretch assignments, and transparent performance management
• Oversee the development of a field-ready HCP promotional platform — including clinical messaging, EAM enablement tools, and channel strategy — built on deep insight into endocrinologist and nephrologist decision-making
• Ensure EAM (Endocrine Account Manager) engagement materials reflect the Calci scientific story with precision, clarity, and promotional compliance
• Lead commercial advisory boards and insight-generation programs to continuously refine HCP strategy and ensure message resonance
• Partner with Market Insights to develop HCP segmentation and targeting frameworks, including tiered engagement models for high-value prescribers
• Guide the patient marketing director in developing a robust DTC and patient-facing strategy, with a focus on diagnosis acceleration, disease education, and treatment adherence for ADH1 patients
• Oversee the commercial patient support ecosystem in partnership with specialty pharmacy and patient services, ensuring a seamless patient journey from identification through persistency
• Champion familial cascade testing as a patient identification lever, ensuring that commercial programs support structured proband communication and relative testing uptake
• Provide strategic direction to two KOL Engagement Leads, ensuring a coordinated, insight-driven KOL plan that spans identification, profiling, advisory board engagement, and speaker bureau development
• Oversee commercial KOL congress strategy and ensure BridgeBio's Calci commercial presence at key endocrine and rare disease meetings is impactful and insight-generating
• Guide the development and governance of the commercial speaker bureau program in alignment with compliance and legal requirements
• Work with Market Insights to build and pressure-test launch forecasting models and establish measurable KPIs across all marketing programs
• Develop and present commercial updates to senior leadership and the Board of Directors, synthesizing brand performance, market dynamics, and strategic pivots
• Establish a metrics-driven culture within the marketing team, driving accountability against leading and lagging brand indicators

Benefits

• Market-leading compensation
• 401(k) with employer match
• Employee Stock Purchase Program (ESPP)
• Pre-tax commuter benefits (transit and parking)
• Referral bonus for hired candidates
• Subsidized lunch and parking on in-office days
• 100% employer-paid medical, dental, and vision premiums for you and your dependents
• Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
• Fertility & family-forming benefits
• Expanded mental health support (therapy and coaching resources)
• Hybrid work model with flexibility
• Flexible, “take-what-you-need” paid time off and company-paid holidays
• Comprehensive paid medical and parental leave to care for yourself and your family
• Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching

What This Job Offers

• Job Type: Full-time
• Career Level: Senior