Senior Director/Executive Director - SMDD Late Stage Small Molecule Chemistry

Eli Lilly and Company • Indianapolis, IN

20h • $172,500 - $253,000 • Onsite

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Product Research and Development (PRD) is at the heart of Lilly’s R&D engine, helping to turn scientific discoveries into life-changing medicines. With our deep technical and scientific expertise, PRD brings together key R&D teams to get our medicines to patients as quickly and effectively as possible. Our work begins at the start of a medicine’s journey, from building a molecule, through developing the right formulation, pioneering patient-friendly drug delivery systems, innovating sustainable manufacturing processes and packaging, supporting clinical trials and finally, helping to get it into the hands of patients. We are there every step of the way. What we do helps make lives better by advancing novel technologies and medicines, speeding up clinical development timelines and reducing costs.

Within PRD, Synthetic Molecule Design and Development (SMDD) is an innovation-focused organization striving to identify, develop, and apply transformative technologies to deliver maximum benefit to our patients. We apply our expertise across the entire lifecycle of an asset ranging from the discovery/development interface through regulatory submission and post-approval changes. We work to improve patient outcomes by delivering safe, scalable, sustainable, and reliable products and processes across a diverse portfolio of synthetic assets including small molecules, peptides, and oligonucleotides. The technical and business solutions that we develop accelerate the delivery of medicines to patients and allow the company to reinvest in the next generation of life-saving therapeutics.

We are seeking a Senior Director - Late Stage Small Molecule Chemistry to provide leadership and delivery of the SMDD late stage small molecule chemistry portfolio. This role will report to the Associate Vice President of Small Molecule Commercialization and be responsible for leading the late stage small molecule chemistry group, including drug substance process development, scale-up, and commercialization across the late stage synthetic small molecule portfolio.

Requirements

• Ph.D. in Organic Chemistry, Synthetic Chemistry, Chemical Engineering, Pharmaceutical Sciences, or related field, or BS with equivalent work experience.
• 10+ years of CMC experience
• Direct experience in late phase development, scale-up, and commercialization of small molecule drug substances, including route selection, process development, and regulatory filings (IND/NDA/CTD Module 3, Section 3.2.S)

Nice To Haves

• Previous supervisory experience
• Excellent communication (written and verbal)
• Exceptional teamwork/interpersonal/leadership/vision
• External network and networking skills
• Expertise in project planning/organization/management
• Talent assessment and recruiting

Responsibilities

• Create a high-performance team culture that operates with clarity of roles, responsibilities, and expectations for both individuals and the team.
• Actively manage internal and external resources, including CMOs and external partners, to drive late stage small molecule chemistry development across the portfolio
• Ensure safety of employees and facilities through implementation of robust safety programs / procedures.
• Recruit, develop, and grow the next generation of scientific leaders.
• Provide strategic guidance to small molecule chemistry teams, including integration and application of new synthetic technologies, continuous and flow chemistry, green chemistry, and emerging process analytical technologies.
• Partner with cross-functional teams including Quality, Regulatory, and manufacturing to ensure seamless integration of development activities.
• Identify opportunities for continual improvement projects that optimize business processes related to late stage small molecule chemistry development and drug substance manufacture.
• Possess deep understanding of the portfolio, project objectives, and how the technical programs and teams are poised to deliver on those objectives.
• Communicate and support execution of SMDD’s technical strategy.
• Evaluate the organization’s strengths and needs and drive appropriate changes.

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree