Senior Director, Commercial Technology

Mineralys Therapeutics

3d•Remote

About The Position

Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. Mineralys is a fully remote company. At Mineralys, every decision we make is driven by a simple truth: the patient is waiting. Our vision is to reduce the burden of cardiorenal diseases by delivering targeted and transformative medications, creating more, healthy days for people with cardiorenal diseases — and commercial technology is a critical enabler of that vision, from launching with precision to sustaining impact at scale. Reporting to the SVP, Digital and Transformation, the Senior Director, Commercial Technology is responsible for standing up the full commercial and medical affairs technology ecosystem from the ground up — on time, fit for purpose from day one, and ready to support an imminent launch. The operating principle is simple: SaaS-first, configuration-led, integration-smart. This is not a role for someone who manages technology from a distance. It demands hands-on engagement, sound architectural judgment, and the ability to move fast without cutting corners.

Requirements

Deep knowledge of the pharma commercial tech landscape, with proven experience building a commercial technology stack from the ground up — ideally more than once.
Direct experience supporting or delivering a pharmaceutical product launch.
Thrives in emerging-company environments — operates at pace, builds from scratch, and makes decisions with limited resources.
Picks the approach that fits the situation — sometimes the proven one, sometimes a new one — based on what gets the commercial team the outcome it needs.
Moves work forward without waiting — raises blockers and risks early to the people who need to know, and organizes the team and vendors so they can keep going without waiting on a single decision-maker.
Sets a clear definition of done before kickoff and measures success by real adoption — what the field, marketing, and medical teams actually use to do their jobs.
Uses AI to take friction out of daily work — territory alignment and call prep for the field, content generation and campaign personalization for marketing ops, literature triage and Medical, Legal, and Regulatory (MLR) review drafting for Medical Affairs — designed into the tools each team already uses, not run as a separate program.
Bachelor's degree in Computer Science, Information Systems, Business, or a related field — or equivalent professional experience.
15+ years of progressive experience in commercial technology, with a significant portion in the pharmaceutical or biotech industry.
Experience operating in an emerging company environment — building at pace, with limited resources, in a greenfield context.

Responsibilities

Own end-to-end implementation of the commercial and medical affairs technology stack — Veeva CRM, marketing automation, omnichannel, market access tools, Medical Affairs systems, and web properties — from first decision through post-launch stability.
Stand up the field force toolkit — Veeva CRM, call planning, sample management, mobile enablement — operational day one.
Partner daily with the Heads of Sales, Marketing, Market Access, and Medical Affairs — translate business needs into technology decisions and help shape the Marketing Technology governance body.
Own the bridge between commercial needs and the data and analytics platform — arbitrate demand and get the right insights to the right people.
Drive adoption across commercial and medical affairs — measured by active use in the field, in marketing, and in medical, not by go-live dates.
Hold the bar on usability — if a tool isn't making the team's job easier, it's not done.
Co-own the technology roadmap with commercial and medical affairs leadership — sequence investments against business priorities and launch milestones.
Own vendor and consultant relationships across the portfolio — set expectations, manage performance, and hold partners to their commitments.
Design compliance into the stack from the start — privacy, promotional review, and HCP obligations are part of how things work, not a step at the end.
Establish clear ownership over the data that runs the commercial and medical organization — HCP master, customer, and consent data — with one source of truth, defined stewards, and governance that holds up under audit.
Initially, this role manages contractors and external vendors delivering against the commercial technology roadmap. The role is expected to grow into direct people management as the function scales post-launch.