Senior Director, Clinical Development
About The Position
In 2015, BridgeBio pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. They build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. Together they define white space, push boundaries, and empower people to solve problems. They are looking for individuals who defy convention to join them and work alongside some of the most respected minds in the industry. Together, they will ask "why not?" and help reengineer the future of biopharma. BridgeBio values curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
Requirements
- MD or equivalent medical degree required
- Board certification in Endocrinology, Nephrology, or a related specialty preferred.
- 5+ years of biotechnology, pharmaceutical, or clinical development experience with increasing medical leadership responsibilities.
- Experience in rare disease, endocrinology, metabolic disease, or chronic hypoparathyroidism drug development strongly preferred.
- Demonstrated expertise in clinical trial design, medical monitoring, protocol development, data interpretation, and regulatory interactions.
- Strong understanding of ICH-GCP, FDA, EMA, and global regulatory requirements.
- Exceptional communication, collaboration, and stakeholder management skills with the ability to influence across functions.
- Patient-focused, intellectually curious, and motivated to thrive in a fast-paced, mission-driven biotechnology environment.
Responsibilities
- Serve as the medical lead for one or more clinical programs, providing strategic and operational leadership across study design, execution, analysis, and reporting.
- Lead cross-functional clinical study teams and provide medical oversight to ensure participant safety, data quality, protocol compliance, and study interpretability.
- Partner with investigators, key opinion leaders, advocacy organizations, and CRO partners to execute high-quality clinical trials.
- Author and review protocols, investigator brochures, clinical study reports, DSURs, informed consent documents, and regulatory submission content.
- Lead medical monitoring activities and contribute to safety review meetings, investigator meetings, and regulatory authority interactions.
- Translate clinical, translational, and nonclinical findings into actionable development strategies and lifecycle plans.
- Represent Calcilytix at scientific congresses and maintain awareness of emerging developments in chronic hypoparathyroidism, endocrinology, and rare disease drug development.
Benefits
- Market-leading compensation
- 401(k) with employer match
- Employee Stock Purchase Program (ESPP)
- Pre-tax commuter benefits (transit and parking)
- Referral bonus for hired candidates
- Subsidized lunch and parking on in-office days
- 100% employer-paid medical, dental, and vision premiums for you and your dependents
- Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
- Fertility & family-forming benefits
- Expanded mental health support (therapy and coaching resources)
- Hybrid work model with flexibility
- Flexible, “take-what-you-need” paid time off and company-paid holidays
- Comprehensive paid medical and parental leave to care for yourself and your family
- Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
- Financial rewards, peer-to-peer recognition, and growth opportunities
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
