Senior Director, Clinical Data Science

Centene CorporationRemote-FL, NE
$185,700 - $352,500Hybrid

About The Position

The Senior Director of Clinical Data Science leads the strategy, development, and deployment of advanced analytics and machine learning models that power clinical decision-making across the organization. This role is responsible for both the development of predictive and AI-driven models that identify clinical risk and prioritize interventions, as well as the rigorous evaluation of clinical programs using causal inference and program evaluation methodologies.

Requirements

  • Bachelor's Degree in a quantitative discipline such as Statistics, Biostatistics, Informatics, Mathematics, Computer Science, Public Health, or Economics or four (4) years of experience in lieu of degree.
  • 8+ years years of data analysis, statistics or related experience.
  • Deep experience developing and deploying predictive models using large healthcare datasets, including claims and/or electronic health record data.
  • Strong expertise in statistical modeling, machine learning, and causal inference methods used to evaluate program effectiveness (e.g., treatment effect modeling, propensity score matching, quasi-experimental methods).
  • Experience evaluating care management, population health, or value-based care programs.
  • Strong programming and data science toolkit including Python, R, SQL, and modern development practices (e.g., Git-based version control).
  • Proven leadership, stakeholder management, and executive communication skills, with the ability to influence clinical, operational, and financial leaders.

Nice To Haves

  • Master's Degree preferred.
  • Experience applying modern machine learning techniques, including deep learning or transformer-based approaches, to healthcare or large-scale data problems strongly preferred.
  • Demonstrated success translating advanced analytics into operational workflows and measurable clinical and financial outcomes strongly preferred.

Responsibilities

  • Lead the enterprise strategy for clinical data science, including predictive modeling, machine learning innovation, and causal evaluation of clinical programs.
  • Develop and deploy advanced models that identify, stratify, and prioritize members for clinical and care management interventions.
  • Oversee development of models for high-risk and rising-risk identification, avoidable utilization, chronic condition progression, and care management prioritization.
  • Advance the organization’s AI capabilities by applying modern machine learning approaches, including deep learning and transformer-based models, to large healthcare datasets.
  • Lead rigorous evaluation of clinical programs using causal inference and quasi-experimental methods such as treatment effect modeling, propensity score matching, and difference-in-differences.
  • Establish analytic frameworks to quantify clinical outcomes, cost savings, and ROI from care management and other intervention programs.
  • Partner with clinical, operational, actuarial, and analytics leaders to translate business and clinical priorities into scalable data science solutions.
  • Ensure models are embedded into operational workflows and aligned with care management capacity, intervention types, and clinical priorities.
  • Establish standards for model governance, monitoring, and performance management to ensure regulatory compliance, fairness, and responsible AI practices.
  • Build, lead, and mentor a high-performing team of data scientists.
  • Performs other duties as assigned.
  • Complies with all policies and standards.

Benefits

  • competitive pay
  • health insurance
  • 401K and stock purchase plans
  • tuition reimbursement
  • paid time off plus holidays
  • a flexible approach to work with remote, hybrid, field or office work schedules
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