Senior Director, Cancer Vaccine Discovery, Infectious Disease

AstraZenecaBoston, MA
$225,901 - $338,851

About The Position

The Head of Cancer Vaccines in Infectious Diseases is responsible for leading efforts to develop and deliver strategies to program the immune system to recognize and eliminate malignant cells. The candidate will build a strategy to leverage the diverse modalities available at AstraZeneca to deploy polyclonal immunity against a range of tumor targets. The candidate will lead a team of scientists and cross-functional experts to build programs. The team will explore different strategies to identify novel candidates, validate neo-antigens, deliver mRNA, amplify immunity, driving early clearance and long-term durable surveillance. The role will be responsible for influencing senior internal stakeholders and manage external and internal collaborations to deliver effective solutions. In addition, the candidate must recruit, develop, and retain a strong, cutting-edge team—fostering a high-performance, innovative culture; building capabilities across immunology, oncology, and translational sciences; and establishing clear operating mechanisms to accelerate decision-making and delivery.

Requirements

  • PhD or equivalent in immunology, oncology, molecular biology, biochemistry or a related discipline with 10+ yrs industry experience
  • Proven experience developing novel immunological approaches to deploy immunity to fight tumors
  • Proven experience with immune profiling, tumor modelling, systems biology, and/or immune oncology
  • Experience working in a cross-functional team to maximize expertise and accelerate success
  • Experience developing and implementing novel methods to support vaccine development
  • Experience supporting or leading interdisciplinary vaccine discovery or development programs
  • Proven experience leading and managing junior colleagues
  • Proven experience developing and controlling budgets
  • Excellent written and verbal communication, business analysis, and consultancy skills

Responsibilities

  • Develop a portfolio of cancer vaccine projects
  • Develop a strategy to support target discovery and product development and ensure cross functional strategic alignment.
  • Lead team to deploy immunity to a range of cancers, leveraging the diverse available platforms.
  • Oversee development of a portfolio of cancer vaccines across early discovery and research pipeline
  • Establish strategic relationships across the organization and functions
  • Oversight and accountability of partnerships with academic or outsourced partners
  • Develop internal and external partnerships to explore combinatorial strategies
  • Create and foster effective relationships with senior and executive stakeholders in Research, Bioprocess Development, Clinical and Translational Medicine and Global Project Teams to ensure alignment across functions
  • Responsible for ensuring all projects within their area and their teams clearly and objectively communicate results, as well as their associated risks, uncertainties and limitations
  • Define the training standards for junior colleagues in line with best practices and principles

Benefits

  • qualified retirement program [401(k) plan]
  • paid vacation and holidays
  • paid leaves
  • health benefits including medical, prescription drug, dental, and vision coverage

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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