Senior Dir, Clinical Pharmacology & Pharmacometrics

Bristol Myers Squibb • San Diego, CA

2d • $229,670 - $306,137 • Hybrid

About The Position

Bristol Myers Squibb is seeking a strategic, scientifically grounded leader to serve as the Senior Director for Clinical Pharmacology & Pharmacometrics. This leader will partner deeply with Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, and Translational Medicine stakeholders to deliver the applications, modeling environments, workflow automation, and governed operational capabilities that support CPP work end to end—from quantitative preclinical-to-clinical bridging through clinical PK/PD, dose and regimen decisions, and submission-support outputs. This role supports the quantitative CPP layer across Research and Development, including pharmacometric workflows, clinical PK/PD systems, modeling platforms, reporting automation, regulatory evidence generation, and the governed operational capabilities required to run these workflows at scale. Reporting to the Vice President, Research Business Insights & Technology, this leader will operate as part of a unified BI&T leadership team and act as a trusted partner to Research and Development leadership. The role carries accountability for the reliability, fit-for-purpose evolution, and long-term scaling of the CPP technology stack and workflow ecosystem, while working in a highly matrixed model with scientific leaders, data teams, lab-platform teams, and regulatory-facing partners.

Requirements

• Ph.D. in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or related quantitative field
• 12+ years in pharmaceutical R&D with deep clinical pharmacology, pharmacometrics, and model-informed drug development experience
• Proven experience implementing or leading CPP applications, PBPK and QSP environments, clinical PK/PD systems, or quantitative workflow automation
• Demonstrated experience supporting regulatory submissions, quantitative reporting, and governed workflows in Development-facing settings
• Experience applying AI/ML or advanced automation to quantitative modeling, reporting, or regulated scientific workflows is preferred
• Director or Senior Director-level leadership experience; experience building and scaling a specialized scientific technology team is a strong differentiator
• Scientific Depth in Clinical Pharmacology and Pharmacometrics — Deep credibility with quantitative scientists and domain leaders across CPP
• Strategic Partnership — Translates scientific and Development needs into practical, integrated technology and workflow solutions
• Operational Leadership — Builds reliable, scalable, inspection-ready environments and support models for critical quantitative workflows
• Regulatory Translation Capability — Understands how quantitative evidence is prepared, reported, reviewed, and used in regulatory settings
• Leadership & Change Attributes
• Strong partnership with senior scientific, clinical, and regulatory leaders
• Comfort operating with regulatory and global Development stakeholders
• Ability to recruit, develop, and retain highly specialized quantitative talent in a competitive market
• Experience navigating matrixed organizations and building credibility quickly
• Commitment to building a collaborative, high-performing culture in a growing team

Nice To Haves

• Experience as a clinical pharmacology or pharmacometrics technology leader inside a top-tier pharmaceutical R&D organization
• Track record of applications, workflows, or platforms that improved dose selection, quantitative decision-making, or regulatory execution in Development-facing settings
• Experience deploying workflow automation, AI-enabled capabilities, or advanced analytics in support of end-to-end CPP modeling, reporting, and decision-support operations
• Demonstrated success building a specialized function from foundational capability to scaled organizational value while operating through strong matrix partnerships

Responsibilities

• Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end
• Partner across Research and Development to integrate CPP workflows with the scientific, data, and operational capabilities required for model-informed drug development
• Own clinical pharmacology and pharmacometrics applications, modeling environments, reporting workflows, and operational support for core CPP use cases
• Ensure operational excellence, reliability, governance, and continuous improvement across modeling environments, clinical PK/PD systems, reporting workflows, and submission-support applications
• Lead automation of priority CPP workflows, including model execution, reporting, simulation, traceability, review, and evidence reuse
• Support quantitative regulatory deliverables through fit-for-purpose tooling, reproducible workflows, and inspection-ready practices
• Partner with Unified Lab & Experimental Platforms, Target & Disease Biology, and In-Vivo & Non-Clinical Pharmacology where translational science, lab systems, diagnostics, biomarker workflows, or bioanalytical capabilities intersect with CPP needs
• Partner with the R&D Data organization on underlying data-product strategy, integration, and fit-for-purpose data access
• Lead and grow a team of scientific technologists, product leaders, and specialized engineers aligned to this domain

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
• All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree