Senior Clinical Scientist

Faeth Therapeutics•San Francisco, CA

1d•Remote

About The Position

Faeth Therapeutics is a clinical-stage oncology company listed on Nasdaq that recently raised $200M in funding. With a strong scientific foundation and a founding team that includes the discoverer of the PI3K pathway, we are advancing PIKTOR, a multi-node PI3K/AKT/mTOR inhibitor program, into late stage development. We are a small, focused team where every person has direct impact — united by a shared commitment to care deeply, create boldly, and never stop learning. The Senior Clinical Scientist is a key scientific leader within the Clinical Development team, responsible for the design, execution, and interpretation of clinical trials across Faeth’s oncology programs. This individual will drive cross-functional collaboration, provide strategic input into clinical development plans, and ensure delivery of high-quality data to support regulatory and scientific objectives. The role requires deep scientific expertise, operational insight, and the ability to influence both internal and external stakeholders.

Requirements

5–8+ years of oncology clinical development experience
Demonstrated experience leading components of interventional clinical trials (Phase 1–3)
Strong expertise in clinical trial design, execution, and data interpretation
Deep understanding of oncology drug development; experience in metabolism, nutrition, or biomarker-driven approaches is a plus
Working knowledge of GCP, ICH guidelines, and global regulatory requirements
Proven ability to lead cross-functional initiatives and influence without authority
Excellent communication, analytical, and problem-solving skills
Comfortable operating in a fast-paced, evolving biotech environment

Nice To Haves

Advanced degree (PhD, PharmD, MS, or equivalent) in life sciences, clinical research, or related field

Responsibilities

Lead the design and development of clinical protocols, amendments, and core study documents (e.g.,IBs, DSURs, SAPs, CRFs)
Lead ongoing review, monitoring, querying and interpretation of clinical data (safety, efficacy, PK/PD, and biomarker endpoints)
Provide leadership across one or more clinical programs, including lifecycle planning
Oversee execution of Phase 1–3 clinical trials in partnership with Clinical Operations, ensuring quality, timelines, and clinical review of data
Serve as a primary clinical point of contact for CROs, vendors, and investigative sites
Identify and proactively mitigate study risks; drive issue resolution across functions
Drive data quality, including oversight of data cleaning, query resolution, and database lock
Ensure alignment between clinical strategy and translational/biomarker plans
Lead contributions to regulatory submissions (INDs, CTAs, briefing documents, responses to health authorities)
Drive preparation of clinical study reports (CSRs), abstracts, manuscripts, and conference presentations
Represent Clinical Development in internal governance meetings and external interactions